Drug Induced Erythema Multiforme: Two Case Series with Review of Literature
ZH01-ZH04
Correspondence
Dr. B.S. Manjunatha,
Department of Oral and Maxillofacial Pathology, K M Shah Dental College & Hospital, Sumandeep Vidyapeeth,
Pipariya-391760, Vadodara, India.
Phone : 91-02668-245266, E-mail : drmanju26@hotmail.com
Erythema multiforme, (EM) an uncommon, acute inflammatory reactive mucocutaneous disorder and primary allergies confined to the oral mucosa. However the subsequent attacks can produce more severe forms of EM involving the skin. Manifestations of EM are varied and present a diagnostic dilemma because infections (particularly herpes simplex and mycoplasma pneumoniae) and drugs seem to predispose towards development of EM. We report two cases of erythema multiforme in which drugs (Dioclofenac sodium & Amoxycilline) seems to be precipitating factor. In addition, the article reviews various aspects of EM as relevant to dental practice and highlight the associated potential etiologic agents, pathogenic mechanisms and therapies.