Childhood Onset Nephrotic Syndrome-A Journey Through Two Pregnancies QD08-QD09
Dr. Shashikiran Umakanth,
Professor and Head, Department of Medicine, Dr. TMA Pai Hospital, Udupi Melaka Manipal Medical College,
Manipal Academy of Higher Education,
Manipal, Karnataka, India.
Nephrotic Syndrome (NS), a unique renal disease complex associated with heavy proteinuria (protein excretion >3.5 gm/day), hypoalbuminemia (<30 gm/L) and peripheral oedema. It is a rare entity in pregnancy, with an incidence of about 0.012-0.025%. There have been very few reports of pregnancy with co-existing NS. We hereby report a case of steroid sensitive childhood onset NS, due to minimal change disease and her course through two pregnancies. While she had a relapse of NS during her first pregnancy, she sailed through her second pregnancy without relapse. Women with NS can have a good maternal and perinatal outcome with multidisciplinary approach. Pregnancy does not always worsen the existing NS by causing a relapse or disease progression.