Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Case report
Table of Contents - Year : 2018 | Month : July | Volume : 12 | Issue : 7 | Page : QD08 - QD09

Childhood Onset Nephrotic Syndrome-A Journey Through Two Pregnancies QD08-QD09

Shashikala K Bhat, Shashikiran Umakanth, Krupa Shah, Ashwini AP, Ravindra Prabhu

Correspondence
Dr. Shashikiran Umakanth,
Professor and Head, Department of Medicine, Dr. TMA Pai Hospital, Udupi Melaka Manipal Medical College,
Manipal Academy of Higher Education,
Manipal, Karnataka, India.
E-mail: shashikiranu@gmail.com

Nephrotic Syndrome (NS), a unique renal disease complex associated with heavy proteinuria (protein excretion >3.5 gm/day), hypoalbuminemia (<30 gm/L) and peripheral oedema. It is a rare entity in pregnancy, with an incidence of about 0.012-0.025%. There have been very few reports of pregnancy with co-existing NS. We hereby report a case of steroid sensitive childhood onset NS, due to minimal change disease and her course through two pregnancies. While she had a relapse of NS during her first pregnancy, she sailed through her second pregnancy without relapse. Women with NS can have a good maternal and perinatal outcome with multidisciplinary approach. Pregnancy does not always worsen the existing NS by causing a relapse or disease progression.