Evaluation of ECG Abnormalities in Patients with Asymptomatic Type 2 Diabetes MellitusCorrespondence Address :
Dr. Rajeev Kumar Gupta,
F-7, Faculty Residence RMCH, Bareilly-243006, Uttar Pradesh, India.
Introduction: Diabetes Mellitus (DM) is the most common chronic disease. DM is considered a Cardiovascular Disease (CVD) risk equivalent. Its macrovascular complications are associated with two-fold increased risk of premature atherosclerotic CVD. Most of the diabetics with cardiovascular involvement are asymptomatic. Electro Cardio Graph (ECG) abnormalities are found to be predictors of silent ischaemia in asymptomatic persons. An abnormal ECG response is associated with statistically significant high risk for cardiac mortality and morbidity.
Aim: The aim of the study was to evaluate ECG changes in asymptomatic Type 2 DM patients.
Materials and Methods: A cross-sectional comparative study was conducted in a tertiary care hospital in North India. One hundred diabetics presenting to Medicine OPD/IPD were included in the study who had no symptoms of heart disease and no diabetic complications. Fifty person with age and sex matched controls were included in the study. Relevant history and physical examination findings were recorded in a protocol. The variables studied were: gender, age, smoking, physical activity, and waist circumference, Body Mass Index (BMI) and blood pressure. Resting ECG was recorded.
Results: Mean age of asymptomatic diabetic patients was 50.3±11.90 years (age range 25-75 years). In this study, none of the control group had ECG abnormality whereas, 26% asymptomatic diabetics had ECG abnormalities. Most of the asymptomatic cases with ECG changes had 5-10 year of duration of diabetes mellitus; 70% patients with ECG changes had poor glycaemic control, increased triglyceride and decreased High Density Lipoprotein (HDL) levels. Most common abnormality observed was ST-T changes, followed by Left Atrial Enlargement (LAE), Left Ventricular Hypertrophy (LVH), Left Bundle Branch Block (LBBB) and Right Bundle Branch Block (RBBB).
Conclusion: ECG changes are present in quarter of asymptomatic Type 2 DM patients. However, nonspecific ST-T changes, LVH and LAE are common.
Cardiovascular disease, Poor glycemic control, Silent angina
Sahil Gupta, Rajeev Kumar Gupta, Malini Kulshrestha, Rajib Ratna Chaudhary. EVALUATION OF ECG ABNORMALITIES IN PATIENTS WITH ASYMPTOMATIC TYPE 2 DIABETES MELLITUS. Journal of Clinical and Diagnostic Research [serial online] 2017 April [cited: 2017 Apr 25 ]; 11:OC39-OC41. Available from
Date of Submission: Oct 18, 2016
Date of Peer Review: Dec 16, 2016
Date of Acceptance: Jan 10, 2017
Date of Publishing: Apr 01, 2017
Financial OR OTHER COMPETING INTERESTS: None.
- PubMed Central® (PMC)New
- Academic Search Complete Database
- Chemical Abstracts Service
- Directory of Open Access Journals (DOAJ)
- Embase & EMbiology
- Google Scholar
- HINARI Access to Research in Health Programme
- Indian Science Abstracts (ISA)
- Journal seek Database
- Open J-Gate
- Popline (reproductive health literature)