Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Case report
Year : 2017 | Month : February | Volume : 11 | Issue : 2 | Page : ED04 - ED05

A Fortuitous Turn of Evidence in an Elderly Female – A Case of Pulmonary Fusariosis

Saraswathy Sreeram, Flora Dorothy Lobo, Vishak Acharya, Vishwas Saralaya

1. Assistant Professor, Department of Pathology, Manipal University, Mangaluru, Karnataka, India. 2. Professor, Department of Pathology, Manipal University, Mangaluru, Karnataka, India. 3. Professor and Head of the Department, Department of Pulmonary Medicine, Manipal University, Mangaluru, Karnataka, India. 4. Associate Professor, Department of Microbiology, Manipal University, Mangaluru, Karnataka, India.

Correspondence Address :
Dr. Saraswathy Sreeram,
Kasturba Medical College, Lighthouse Hill Road, Hampankatta Pin:575001, Mangaluru, Karnataka, India.
Email: swameeram@gmail.com

Abstract

Pulmonary mycosis is seen infrequently in our country. It is more common in the immunocompromised. The infections caused by less known species like Fusarium have been found to be increasing in incidence in other parts of the world. We hereby report its occurrence in a 79-year-old, non-immunocompromised female who presented with pyrexia of unknown origin. Her Alanine Phosphatase (ALP) and Lactate Dehydrogenase (LHD) levels were raised. CT scan showed interstitial thickening in subpleural aspect of lungs and multiple enlarged lymph nodes in mediastinum. Liver showed multiple hypodense lesions. Metastasis was suspected for which Fine Needle Aspiration Cytology (FNAC) of liver was done which showed foci of regenerative hepatocytes with desmoplastic stromal tissue fragments and negative for tumour. Her Alpha Fetoprotein (AFP) was normal. The bronchial tree cytology showed endobronchial cells, dust-laden macrophages and chronic inflammatory cells along with fungi on Pap smear studies. This was confirmed by culture that grew Fusarium species after one week of incubation. The acutely branching septate hyphae of Fusarium species are identical to those of Aspergillus species. In a patient who has a disseminated infection with a septate fungus, growth in culture is important to identify the specific organism and subsequently treatment with appropriate antifungals. In cases like ours, where the infection simulates malignancy, it is even more important to make the correct diagnosis to give the appropriate treatment.

Keywords

Cytology, Filamentous fungi, Fusarium, Immunocompetent, Lung cancer

How to cite this article :

Saraswathy Sreeram, Flora Dorothy Lobo, Vishak Acharya, Vishwas Saralaya. A FORTUITOUS TURN OF EVIDENCE IN AN ELDERLY FEMALE – A CASE OF PULMONARY FUSARIOSIS. Journal of Clinical and Diagnostic Research [serial online] 2017 February [cited: 2017 Mar 24 ]; 11:ED04-ED05. Available from
http://jcdr.net/back_issues.asp?issn=0973-709x&year=2017&month=February&volume=11&issue=2&page=ED04-ED05&id=9191

DOI and Others

DOI: 10.7860/JCDR/2017/24736.9191


Date of Submission: Oct 14, 2016
Date of Peer Review: Oct 31, 2016
Date of Acceptance: Nov 28, 2016
Date of Publishing: Feb 01, 2017


Financial OR OTHER COMPETING INTERESTS: None.

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