Benign Fibrous Histiocytoma: An Uncommon PresentationCorrespondence Address :
Dr. Sagarika Sarkar,
Junior Resident, Department of Pathology, NRS Medical College and Hospital,
138, AJC Bose Road, Kolkata-700014, West Bengal, India.
Intracranial fibrous histiocytomas are rare; Benign Fibrous Histiocytoma (BFH) being uncommon than its malignant counterpart. BFH comprises fibroblasts and histiocytes without any nuclear pleomorphism or atypia. We present a case of a 42-year-old male who had swelling over the occipital region for the past five years, which progressively increased in size. He developed headache, dizziness, and gait disturbance over the last six months. Computed tomographic scan revealed a posterior fossa space-occupying lesion. Fine-needle aspiration cytology from the swelling revealed spindled fibroblasts along with histiocytes and multinucleated giant cells. Later, histopathology showed presence of spindle-shaped cells in storiform pattern admixed with histiocytes and giant cells. The giant cells and histiocytes were immunopositive for CD68 and spindled cells were positive for vimentin, but immunonegative for CD34, epithelial membrane antigen, CD1a and S100. The final diagnosis was intracranial BFH. We present this case because of its extreme rarity and unusual location.
Intracranial, Meninges, Middle-aged man
Sagarika Sarkar, Moumita Maiti, Palas Bhattacharyya, Ranu Sarkar. BENIGN FIBROUS HISTIOCYTOMA:
AN UNCOMMON PRESENTATION. Journal of Clinical and Diagnostic Research [serial online] 2017 July [cited: 2017 Jul 21 ]; 11:ED08-ED09. Available from
Date of Submission: Apr 10, 2017
Date of Peer Review: May 01, 2017
Date of Acceptance: May 03, 2017
Date of Publishing: Jul 01, 2017
Financial OR OTHER COMPETING INTERESTS: None.
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