Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Case report
Year : 2017 | Month : July | Volume : 11 | Issue : 7 | Page : FD01 - FD02

A Rare Instance of Levofloxacin Induced Myoclonus

Sushil Kiran Kunder, A. Avinash, Veena Nayak, Amod Tilak

1. Postgraduate, Department of Pharmacology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India. 2. Postgraduate, Department of Pharmacology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India. 3. Associate Professor, Department of Pharmacology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India. 4. Postgraduate, Department of Pharmacology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.

Correspondence Address :
Dr. Veena Nayak,
Associate Professor, Department of Pharmacology, Kasturba Medical College,
Manipal University, Manipal-576104, Karnataka, India.
E-mail: veena.nayak@manipal.edu

Abstract

Levofloxacin is a widely used fluoroquinolone, mainly as a respiratory antimicrobial agent. It is employed as a second line therapeutic modality in pulmonary tuberculosis as well. The drug has been in use for ages, and is known to be both efficacious and safe. However, it is not free of adverse effects. The most dangerous ones are those involving the Central Nervous System (CNS). Although rare, levofloxacin can cause involuntary movements like chorea and myoclonus. Here by, we present a case of an elderly male patient who developed reversible myoclonus/chorea after a course of levofloxacin (which was initiated as part of his anti-tubercular therapy) following the development of peripheral neuropathy secondary to isoniazid.

Keywords

Chorea, Fluoroquinolones, Involuntary movements

How to cite this article :

Sushil Kiran Kunder, A. Avinash, Veena Nayak, Amod Tilak. A RARE INSTANCE OF LEVOFLOXACIN INDUCED MYOCLONUS. Journal of Clinical and Diagnostic Research [serial online] 2017 July [cited: 2017 Jul 21 ]; 11:FD01-FD02. Available from
http://jcdr.net/back_issues.asp?issn=0973-709x&year=2017&month=July&volume=11&issue=7&page=FD01-FD02&id=10189

DOI and Others

DOI: 10.7860/JCDR/2017/27005.10189

Date of Submission: Jan 25, 2017
Date of Peer Review: Feb 21, 2017
Date of Acceptance: Apr 20, 2017
Date of Publishing: Jul 01, 2017

Financial OR OTHER COMPETING INTERESTS: None.

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