Indian Perspectives on Graft Materials Used for Repair of Tympanic MembraneCorrespondence Address :
Dr. Manu Malhotra,
Associate Professor, Department of Otolaryngology, AIIMS, Rishikesh, ¾, Type IV, AIIMS,
Veerbhadra Marg, Rishikesh-243203, Uttarakhand, India.
Introduction: Repair of Tympanic Membrane (TM) is one of the most common surgeries performed by the otologists. Literature reveals that Indian surgeons have contributed substantially in the research on techniques and graft materials used for the repair of tympanic membrane, though no review has been written so far highlighting their contributions.
Aim: To summarize and analyse the contributions of Indian authors who have used different graft materials for repair of TM and their studies listed in Medline search.
Materials and Methods: A literature review was conducted using a Medline search using keywords of ‘myringoplasty’ and ‘tympanoplasty’ with ‘India’ on 30th June 2016. A total of 243 articles were found listed onwards from year 1998. Out of these 50 articles in which type 1 tympanoplasty or myringoplasty was performed using different graft materials were selected. The content of each abstract was studied in order to identify studies related to topic.
Results: Authors have experimented with a variety of tissues as graft materials. Temporalis Fascia (TF) has been most widely used in 58.6% studies as graft material. The next popular graft is tragal perichondrium. The graft take up rates varied from 68.5% to 100%, while method of reporting of hearing gain in most studies was inconsistent amongst studies, though most studies have reported achievement of serviceable hearing of < 25 dB in most patients.
Conclusion: TF was the most prefered material due to anatomic proximity, light material and strength. It was followed in popularity by tragal perichondrium and tragal cartilage. All graft materials have given satisfactory hearing results.
Accelerated failure time, Extended cox models, Frailty models, Multistate models
Manu Malhotra, Saurabh Varshney, Rashmi Malhotra, Poonam Joshi. INDIAN PERSPECTIVES ON GRAFT MATERIALS USED FOR REPAIR OF TYMPANIC MEMBRANE. Journal of Clinical and Diagnostic Research [serial online] 2017 July [cited: 2017 Sep 20 ]; 11:ME01-ME06. Available from
Date of Submission: Dec 24, 2016
Date of Peer Review: Jan 27, 2017
Date of Acceptance: Mar 30, 2017
Date of Publishing: Jul 01, 2017
Financial OR OTHER COMPETING INTERESTS: None.
- PubMed Central® (PMC)New
- Academic Search Complete Database
- Chemical Abstracts Service
- Directory of Open Access Journals (DOAJ)
- Embase & EMbiology
- Google Scholar
- HINARI Access to Research in Health Programme
- Indian Science Abstracts (ISA)
- Journal seek Database
- Open J-Gate
- Popline (reproductive health literature)