Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Case report
Year : 2017 | Month : July | Volume : 11 | Issue : 7 | Page : ZD10 - ZD12

Denovo High Grade Salivary Duct Carcinoma: A Case Report and Review of Literature

Heena Zainab, Ameena Sultana, Pramod Jahagirdar

1. Professor and Head, Department of Oral and Maxillofacial Pathology and Microbiology, Al Badar Rural Dental College and Hospital, Kalaburgi, Karnataka, India. 2. Postgraduate Student, Department of Oral and Maxillofacial Pathology and Microbiology, Al Badar Rural Dental College and Hospital, Kalaburgi, Karnataka, India. 3. Professor, Department of Oral and Maxillofacial Pathology and Microbiology, Al Badar Rural Dental College and Hospital, Kalaburgi, Karnataka, India.

Correspondence Address :
Dr. Heena Zainab
Professor and Head, Department of Oral and Maxillofacial Pathology and Microbiology,
Al Badar Rural Dental College and Hospital, Kalaburgi-585102, Karnataka, India.
E-mail: hinazainab1@yahoo.co.in

Abstract

Salivary Duct Carcinoma (SDC) is a distinctive and clinically aggressive adenocarcinoma of salivary origin. It arises from the ductal epithelium, predominantly occurring in the major salivary glands, especially the parotid gland. Here, we report a case of an extensive salivary gland pathology involving the right side of face, possibly arising from the parotid gland in a 25-year-old male patient. On routine histopathology, the tumour mass revealed a papillary pattern of neoplastic ductal epithelial cells showing comedo-like-central necrosis. Immunohistochemical staining showed tumour cells in the infiltrative component to be diffusely immunopositive for cytokeratin-7 and Her-2, confirming the diagnosis of SDC. This paper presents a case report on salivary duct carcinoma and highlights a review on histological variants of salivary duct carcinoma.

Keywords

Comedo-like, Histopathology, Immunohistochemical markers, Parotid gland, Tumour

How to cite this article :

Heena Zainab, Ameena Sultana, Pramod Jahagirdar. DENOVO HIGH GRADE SALIVARY DUCT CARCINOMA: A CASE REPORT AND REVIEW OF LITERATURE. Journal of Clinical and Diagnostic Research [serial online] 2017 July [cited: 2017 Sep 20 ]; 11:ZD10-ZD12. Available from
http://jcdr.net/back_issues.asp?issn=0973-709x&year=2017&month=July&volume=11&issue=7&page=ZD10-ZD12&id=10210

DOI and Others

DOI: 10.7860/JCDR/2017/29195.10210



Date of Submission: Apr 18, 2017
Date of Peer Review: Jun 03, 2017
Date of Acceptance: Jun 08, 2017
Date of Publishing: Jul 01, 2017


Financial OR OTHER COMPETING INTERESTS: None.

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