Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Year : 2017 | Month : May | Volume : 11 | Issue : 5 | Page : EC05 - EC08

Erythrocytes and Platelets: A Critical Analysis of their Ontogenic Relationship through Automated Parameters

Deepak Kumar, Padmapriya Kasukurti, Srinivasa Murthy

1. Associate Professor, Department of Pathology, ESIC Medical College and PGIMSR, Bangalore, Karnataka, India. 2. Assistant Professor, Department of Pathology, Sapthagiri Institute of Medical Sciences and Research Centre, Bangalore, Karnataka, India. 3. Professor and Head, Department of Pathology, ESIC Medical College and PGIMSR, Bangalore, Karnataka, India.

Correspondence Address :
Dr. Deepak Kumar,
Associate Professor, Department of Pathology, ESIC Medical College and PGIMSR,
Rajajinagar, Bangalore, Karnataka, India.
E-mail: dkgajare@gmail.com

Abstract

Introduction: Erythrocytes and platelets share an intimate development history, due to which special interest is centered on their relationship. Mature Red Blood Cells (RBCs) and platelets show a similar physiological rhythm, and are concurrently involved in numerous pathologic states.

Aim: To identify subtle relationships between various RBC and platelet parameters with an objective to analyse if a linear correlation co-exists between and among them in physiological/pathological states.

Materials and Methods: A prospective analysis of 1250 EDTA blood samples was conducted. The five RBC parameters (RBC count, HCT, MCV, RDW, Hb) and four platelet parameters (platelet count, PCT, MPV, PDW) obtained from each case were statistically analysed for linear dependence.

Results: A statistically significant direct linear relationship was found between RDW with platelet count and PCT. A statistically significant inverse linear relationship was noticed between the following parameters: i) HCT with platelet count and PCT; ii) MCV with platelet count and PCT; iii) Haemoglobin and platelet count.

Conclusion: A linear correlation, either direct or inverse, was seen among various parallel RBC and platelet parameters.

Keywords

Automation, Ontogeny, Platelet parameters, Red blood cell parameters

How to cite this article :

Deepak Kumar, Padmapriya Kasukurti, Srinivasa Murthy. ERYTHROCYTES AND PLATELETS: A CRITICAL ANALYSIS OF THEIR ONTOGENIC RELATIONSHIP THROUGH AUTOMATED PARAMETERS. Journal of Clinical and Diagnostic Research [serial online] 2017 May [cited: 2017 May 29 ]; 11:EC05-EC08. Available from
http://jcdr.net/back_issues.asp?issn=0973-709x&year=2017&month=May&volume=11&issue=5&page=EC05-EC08&id=9807

DOI and Others

DOI: 10.7860/JCDR/2017/25153.9807


Date of Submission: Nov 10, 2016
Date of Peer Review: Dec 12, 2016
Date of Acceptance: Jan 21, 2017
Date of Publishing: May 01, 2017


Financial OR OTHER COMPETING INTERESTS: As declared above.

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