Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

Users Online : 20515

Case report
Year : 2017 | Month : May | Volume : 11 | Issue : 5 | Page : ED09 - ED11

Pure Primary Extragonadal Retroperitoneal Yolk Sac Tumour in a Young Child: A Case Report

Vineeth G Nair, H S Kiran, Shanthala P R

1. Junior Resident, Department of Pathology, Yenepoya Medical College, Mangalore, Karnataka, India. 2. Assistant Professor, Department of Pathology, Yenepoya Medical College, Mangalore, Mangalore, India. 3. Associate Professor, Department of Pathology, Yenepoya Medical College, Mangalore, Karnataka, India.

Correspondence Address :
Dr. Vineeth G Nair,
Room no.412, "A" Block, Gardyenia PG Hostel Yenepoya University Campus,
Deralakatte, Mangalore-575022, Karnataka, India.
E-mail: dr_vgn@yahoo.co.in

Abstract

Germ Cell Tumours (GCTs) in children are uncommon, constituting approximately only 3% of all malignancies in children younger than 15 years of age. Primary extragonadal GCTs constitute only 1-5% of all germ cell tumours and a retroperitoneal site is seen only in 4% of all extragonadal GCTs. Extragonadal GCTs arise from local transformation of primordial germ cells which have been misplaced during the migration of these cells through the midline dorsal mesentery in the fourth-sixth week of embryogenesis. GCTs in children show remarkable variability in age, site, presentation and histology. This is the case of a three-year-old male child who presented with a history of an abdominal swelling which was rapidly progressive in nature. Radiology showed a large retroperitoneal mass and lesions in the liver. Histopathology, immunohistochemistry and serum Alpha-fetoprotein (AFP) values confirmed a diagnosis of pure primary extragonadal yolk sac tumour.

Keywords

Alpha- fetoprotein, Germ cell tumours, Schiller–Duval bodies

How to cite this article :

Vineeth G Nair, H S Kiran, Shanthala P R . PURE PRIMARY EXTRAGONADAL RETROPERITONEAL YOLK SAC TUMOUR IN A YOUNG CHILD: A CASE REPORT. Journal of Clinical and Diagnostic Research [serial online] 2017 May [cited: 2017 Apr 25 ]; 11:ED09-ED11. Available from
http://jcdr.net/back_issues.asp?issn=0973-709x&year=2017&month=May&volume=11&issue=5&page=ED09-ED11&id=9781

DOI and Others

DOI: 10.7860/JCDR/2017/24892.9781


Date of Submission: Oct 18, 2016
Date of Peer Review: Nov 03, 2016
Date of Acceptance: Dec 11, 2016
Date of Publishing: May 01, 2017


Financial OR OTHER COMPETING INTERESTS: None.

JCDR is now Monthly and more widely Indexed .
  • PubMed Central® (PMC)New
  • Academic Search Complete Database
  • Chemical Abstracts Service
  • Directory of Open Access Journals (DOAJ)
  • EBSCOhostNew
  • Embase & EMbiology
  • Google Scholar
  • HINARI Access to Research in Health Programme
  • Indian Science Abstracts (ISA)
  • Journal seek Database
  • Open J-Gate
  • Popline (reproductive health literature)
  • SCOPUS
  • www.omnimedicalsearch.com