Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Case report
Year : 2017 | Month : May | Volume : 11 | Issue : 5 | Page : ND01 - ND02

Intracorneal Amphotericin B Injection in a Case of Indolent Candidal Keratitis

Jyoti Deswal, Sudesh Kumar Arya

1. Senior Resident, Department of Ophthalmolgy, GMCH, Chandigarh, India. 2. Professor, Department of Ophthalmology, GMCH, Chandigarh, India.

Correspondence Address :
Dr. Jyoti Deswal,
Senior Resident, Department of Ophthalmolgy, H.NO. 25/10-A, Jasbir Colony (Near Sheela By-Pass), Rohtak-124001,
Haryana, India.


Ocular candidiasis is one of the opportunistic infection occurring in human body. Pathogenesis wise, Candida is very virulent and slow growing organism. We report a case of 76-year-old female with left eye candidal stromal abscess, not responding to topical and oral antifungal drugs. Patient was administered intrastromal amphotericin B injection in the affected eye. Four midstromal injections were given in the areas surrounding the corneal abscess. A total of approximately 0.05 mL of amphotericin B, 5 µg per 0.1 mL, was administered. Within next four weeks, the eye became completely quiet with healed epithelial defect and corneal scarring. Intracorneal injection of amphotericin B is a safe and effective treatment option for recurrent and recalcitrant fungal infections.


Abscess, Candida, Intrastromal, Photophobia

How to cite this article :

Jyoti Deswal, Sudesh Kumar Arya. INTRACORNEAL AMPHOTERICIN B INJECTION IN A CASE OF INDOLENT CANDIDAL KERATITIS. Journal of Clinical and Diagnostic Research [serial online] 2017 May [cited: 2017 Jun 25 ]; 11:ND01-ND02. Available from

DOI and Others

DOI: 10.7860/JCDR/2017/23249.9774

Date of Submission: Aug 03, 2016
Date of Peer Review: Nov 29, 2016
Date of Acceptance: Feb 05, 2017
Date of Publishing: May 01, 2017


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