Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Case report
Year : 2017 | Month : September | Volume : 11 | Issue : 9 | Page : ED03 - ED05

An Alpha Fetoprotein Producing Gastric Tumor with Yolk Sac, Hepatoid and Papillary Adenocarcinoma Components

Archana Lakshmanan, Ann Kurian, Annapurneswari Subramanyan, Ayyappan Srinivasan

1. Junior Consultant, Department of Histopathology, Apollo Hospitals, Chennai, Tamil Nadu, India. 2. Senior Consultant, Department of Histopathology, Apollo Hospitals, Chennai, Tamil Nadu, India. 3. Senior Consultant, Department of Histopathology, Apollo Hospitals, Chennai, Tamil Nadu, India. 4. Senior Consultant, Department of Surgical Oncology, Apollo Hospitals, Chennai, Tamil Nadu, India.

Correspondence Address :
Dr. Archana Lakshmanan,
New No.6, Old No.24, Cenotaph Road, Teynampet, Chennai-600035, Tamil Nadu, India.
E-mail : mrithulaarchana@gmail.com

Abstract

Alpha Fetoprotein (AFP) producing gastric carcinomas are very rare and have unique clinicopathological features and an extremely poor prognosis. Here, we report a case of AFP producing gastric carcinoma with three distinct histomorphologic patterns such as yolk sac like, hepatoid, tubular and papillary adenocarcinoma components. The uniqueness of this case is absence of metastases and associated findings such as fundic gland polyposis with varying degrees of dysplasia, gastric and duodenal well differentiated neuroendocrine tumour and rectal ganglioneuroma. The patient is symptom free as of two and half year’s postoperative period. AFP producing gastric tumours although rare, need to be identified as it is known to carry poor prognosis.

Keywords

Gastric carcinoma, Stomach, Tumour marker

How to cite this article :

Archana Lakshmanan, Ann Kurian, Annapurneswari Subramanyan, Ayyappan Srinivasan. AN ALPHA FETOPROTEIN PRODUCING GASTRIC TUMOR WITH YOLK SAC, HEPATOID AND PAPILLARY ADENOCARCINOMA COMPONENTS. Journal of Clinical and Diagnostic Research [serial online] 2017 September [cited: 2017 Nov 22 ]; 11:ED03-ED05. Available from
http://jcdr.net/back_issues.asp?issn=0973-709x&year=2017&month=September&volume=11&issue=9&page=ED03-ED05&id=10546

DOI and Others

DOI: 10.7860/JCDR/2017/29454.10546

Date of Submission: Apr 27, 2017
Date of Peer Review: May 22, 2017
Date of Acceptance: Jun 21, 2017
Date of Publishing: Sep 01, 2017

FINANCIAL OR OTHER COMPETING INTERESTS: None.

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