Approach to a Pregnant Woman with Anti D + Anti C Reactivity Pattern: A Diagnostic ConundrumCorrespondence Address :
Dr. Deeksha Singh,
C1/04, Mangal Apartments, Vasundhara Enclave-110096, Delhi, India.
The Rhesus G antigen is present on all RBCs that are C+ and also on most D+ RBCs. Due to this co-distribution of G with either C or D antigen, it mimics a reactivity pattern of anti C + anti D on Indirect Antiglobulin Test (IAT), though the role of Anti G in causing Hemolytic Disease of Newborn (HDN) is controversial. The differentiation of anti D, anti C, and anti G is essential particularly in pregnant females. We hereby report a rare case of anti G with anti D and anti C in a pregnant woman with emphasis on approach to identify anti D+C+G and its implications.
Alloimmunisation, Anti D, Anti C, Anti G, Haemolytic, Irregular erythrocyte antibodies, Pregnancy
Preeti Rai, Geetika Sharma, Deeksha Singh, Jyoti Garg. APPROACH TO A PREGNANT WOMAN WITH ANTI D + ANTI C REACTIVITY PATTERN: A DIAGNOSTIC CONUNDRUM. Journal of Clinical and Diagnostic Research [serial online] 2017 September [cited: 2017 Nov 20 ]; 11:ED06-ED08. Available from
Date of Submission: Feb 28, 2017
Date of Peer Review: Apr 25, 2017
Date of Acceptance: May 08, 2017
Date of Publishing: Sep 01, 2017
FINANCIAl OR OTHER COMPETING INTERESTS: None.
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