Aspects of Evolving Genito Urinary Tuberculosis-A Profile of Genito Urinary Tuberculosis (GUTB) in 110 PatientsCorrespondence Address :
Dr. Sriram Krishnamoorthy,
Department of Urology, Sri Ramachandra Medical College, Porur, Chennai - 600116, Tamil Nadu, India.
Introduction: Genito Urinary Tuberculosis (GUTB) is a widespread disease seen in urology practice. The true incidence and prevalence of GUTB is difficult to estimate because a large number of patients remain asymptomatic.
Aim: To recognize typical and atypical clinical and radiological features of tuberculosis and to emphasize the need for diagnosing GUTB early.
Materials and Methods: This was a retrospective study conducted in 110 cases of GUTB diagnosed and treated in two teaching institutions over a period of three years, from July 2002 to June 2005. A detailed history, thorough clinical examination, urine examination, culture for tubercle bacillus, imaging studies, cystoscopy and histological and serological examination were done to arrive at a diagnosis
Results: Fifty six patients (51%) were in the age group of 21-40 years. The male: female ratio was 1.4: 1. Loin pain was the most common symptom observed in 27% of the patients. Intravenous Urogram (IVU) revealed non-visulalised kidney in 25 patients (23%), hydronephrosis or hydrouretero nephrosis in 34 patients (31%) and distortion, cavitation or scarring of the calyces in 16 patients (14.5%). Five of them had thimble bladder. In 14 patients, IVU appeared normal. About 28 patients (25%) were treated conservatively with anti tuberculosis therapy. Twenty one of them (19%) underwent Nephrectomy and 10 patients had reconstructive procedures.
Conclusion: A peculiarity of most of our patients was a late presentation with advanced disease. Most patients were asymptomatic or ignorant. Slow but continuous infection causes a destruction of renal parenchyma and the healing process leads to renal parenchymal loss. If identified early and treated appropriately, GUTB is a curable condition.
Acid fast bacilli, Hydronephrosis, Nephrectomy, Tubercle bacillus, Tuberculoma
Sriram Krishnamoorthy, Velmurugan Palaniyandi, Natarajan kumaresan, Sivasankar Govindaraju, Jayaganesh Rajasekaran, Ilangovan Murugappan, et al.. ASPECTS OF EVOLVING GENITO URINARY TUBERCULOSIS-A PROFILE OF GENITO URINARY TUBERCULOSIS (GUTB) IN 110 PATIENTS. Journal of Clinical and Diagnostic Research [serial online] 2017 September [cited: 2017 Sep 23 ]; 11:PC01-PC05. Available from
Date of Submission: Dec 07, 2016
Date of Peer Review: Jan 30, 2017
Date of Acceptance: Feb 24, 2017
Date of Publishing: Sep 01, 2017
FINANCIAL OR OTHER COMPETING INTERESTS: None.
- PubMed Central® (PMC)New
- Academic Search Complete Database
- Chemical Abstracts Service
- Directory of Open Access Journals (DOAJ)
- Embase & EMbiology
- Google Scholar
- HINARI Access to Research in Health Programme
- Indian Science Abstracts (ISA)
- Journal seek Database
- Open J-Gate
- Popline (reproductive health literature)