Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Case report
Year : 2017 | Month : December | Volume : 11 | Issue : 12 | Page : XD01 - XD03

An Unusual Case of Primary Plasma Cell Leukaemia Mimicking Acute Leukaemia: A Case Report and Review of Literature

Abha Singla, Monica Gupta

1. Senior Resident, Department of Oncopathology, Delhi State Cancer Institute, Delhi, India. 2. Assistant Professor, Department of Oncopathology, Delhi State Cancer Institute, Delhi, India.

Correspondence Address :
Dr. Monica Gupta,
Assistant Professor, Department of Oncopathology, Delhi State Cancer Institute, Delhi-110095, India.


Plasma Cell Leukaemia (PCL) is rare and an aggressive disease accounting for only 2-3% of all plasma cell dyscrasias. Diagnosis is made when there are more than 2x109/L plasma cells in the peripheral blood or monoclonal plasmacytosis more than 20% of the Total Leucocyte Count (TLC). We report a case of 58-year-old male with history of high grade fever, generalized weakness and giddiness for two to three months. Peripheral blood film revealed marked leucocytosis with 88% of atypical cells resembling blasts. Flow cytometric immunophenotyping confirmed plasmacytic lineage. Bone marrow was planned but the patient deteriorated very rapidly and died within 3 days. PCL has no definitive treatment and has a dismal prognosis, requiring more extensive data to improve the disease course.


Flowcytometric, Immunophenotyping, Monoclonal

How to cite this article :

Abha Singla, Monica Gupta. AN UNUSUAL CASE OF PRIMARY PLASMA CELL LEUKAEMIA MIMICKING ACUTE LEUKAEMIA: A CASE REPORT AND REVIEW OF LITERATURE. Journal of Clinical and Diagnostic Research [serial online] 2017 December [cited: 2018 Mar 19 ]; 11:XD01-XD03. Available from

DOI and Others

DOI: 10.7860/JCDR/2017/31003.10948

Date of Submission: Jun 24, 2017
Date of Peer Review: Aug 30, 2017
Date of Acceptance: Sep 13, 2017
Date of Publishing: Dec 01, 2017


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