An Unusual Case of Primary Plasma Cell Leukaemia Mimicking Acute Leukaemia: A Case Report and Review of LiteratureCorrespondence Address :
Dr. Monica Gupta,
Assistant Professor, Department of Oncopathology, Delhi State Cancer Institute, Delhi-110095, India.
Plasma Cell Leukaemia (PCL) is rare and an aggressive disease accounting for only 2-3% of all plasma cell dyscrasias. Diagnosis is made when there are more than 2x109/L plasma cells in the peripheral blood or monoclonal plasmacytosis more than 20% of the Total Leucocyte Count (TLC). We report a case of 58-year-old male with history of high grade fever, generalized weakness and giddiness for two to three months. Peripheral blood film revealed marked leucocytosis with 88% of atypical cells resembling blasts. Flow cytometric immunophenotyping confirmed plasmacytic lineage. Bone marrow was planned but the patient deteriorated very rapidly and died within 3 days. PCL has no definitive treatment and has a dismal prognosis, requiring more extensive data to improve the disease course.
Flowcytometric, Immunophenotyping, Monoclonal
Abha Singla, Monica Gupta. AN UNUSUAL CASE OF PRIMARY PLASMA CELL LEUKAEMIA MIMICKING ACUTE LEUKAEMIA:
A CASE REPORT AND REVIEW OF LITERATURE. Journal of Clinical and Diagnostic Research [serial online] 2017 December [cited: 2018 Mar 19 ]; 11:XD01-XD03. Available from
Date of Submission: Jun 24, 2017
Date of Peer Review: Aug 30, 2017
Date of Acceptance: Sep 13, 2017
Date of Publishing: Dec 01, 2017
FINANCIAL OR OTHER COMPETING INTERESTS: None.
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