Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Year : 2018 | Month : August | Volume : 12 | Issue : 8 | Page : CC13 - CC16

The Effect of Vitamin D3 on Depression in Iranian Women

Zeinab Mehrabani Far, Mehdi Rahnema, Hussein Qafelehbashi

1. Postgraduate Student, Department of Clinical Psychology, Faculty of Education and Psychology, Zanjan Branch, Islamic Azad University, Zanjan, Iran. 2. Associate Professor, Department of Physiology, Zanjan Branch, Islamic Azad University, Zanjan, Iran. 3. Assistant Professor, Department of Clinical Psychology, Faculty of Medicine, Qazvin university of Medical Sciences, Qazvin, Iran.

Correspondence Address :
Zeinab Mehrabanifar,
Postgraduate Student, Department of Clinical Psychology, Faculty of Education and Psychology, Zanjan Branch, Islamic Azad University, Zanjan, Iran.
E-mail: md.yar88@yahoo.com

Abstract

Introduction: Depression is one of the most common psychiatric illnesses that it associated with a variety of symptoms, high rates of relapse, and many physical and psychological disorders.

Aim: To determine the effect of vitamin D3 supplements on depression in women referred to health centres in Qazvin, Iran.

Materials and Methods: Overall, 374 patients were evaluated with Beck's depression test. A total of 65 patients were included in the study after they were diagnosed with moderate and severe depression. Individuals with moderate depression were divided into two groups: 1) Cognitive Behavioural Therapy (CBT); and 2) CBT plus vitamin D3 (50,000 units of eight tablets for eight weeks). Subjects with severe depression were divided into two groups: 1) drug therapy; and 2) drug therapy plus vitamin D3. Beck's test and vitamin D3 blood sample measurements were performed before and eight weeks after intervention. Independent sample t-test was used to compare the means of control and intervention groups.

Results: Depression scores of patients in post-test stage were significantly lower than depression scores of patients in pre-test stage in all intervention methods (p<0.01). Mean depression score (11.42.5) of patients in post-test stage of intervention with CBT plus vitamin D3 was significantly lower than the depression score (14.72.7) of patients in post-test stage of intervention with CBT (p<0.05). The difference of mean depression scores in post-test stage of drug therapy (20.43.7) and drug therapy plus vitamin D3 (15.83.3) intervention methods was significant (p<0.05).

Conclusion: The use of vitamin D3 supplements can be helpful in the treatment of depression in women.

Keywords

Counseling, Drug therapy, Improvement

How to cite this article :

Zeinab Mehrabani Far, Mehdi Rahnema, Hussein Qafelehbashi. THE EFFECT OF VITAMIN D3 ON DEPRESSION IN IRANIAN WOMEN. Journal of Clinical and Diagnostic Research [serial online] 2018 August [cited: 2018 Jul 22 ]; 12:CC13-CC16. Available from
http://jcdr.net/back_issues.asp?issn=0973-709x&year=2018&month=August&volume=12&issue=8&page=CC13-CC16&id=11870

DOI and Others

DOI: 10.7860/JCDR/2018/35716.11870

Date of Submission: Jan 25, 2018
Date of Peer Review: Mar 20, 2018
Date of Acceptance: May 23, 2018
Date of Publishing: Aug 01, 2018

FINANCIAL OR OTHER COMPETING INTERESTS: NONE.

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