Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Case report
Year : 2018 | Month : January | Volume : 12 | Issue : 1 | Page : OD04 - OD06

A case of Insulinoma With Improved Reactive Hypoglycemia After Operation

Shunsuke Funazaki, Hodaka Yamada, Yuko Matsumoto, Kazuo Hara

1. Clinical Fellow, Division of Endocrinology and Metabolism, Jichi Medical University Saitama Medical Center, Saitama, Japan. 2. Assistant Professor, Division of Endocrinology and Metabolism, Jichi Medical University Saitama Medical Center, Saitama, Japan. 3. Clinical Fellow, Division of Endocrinology and Metabolism, Jichi Medical University Saitama Medical Center, Saitama, Japan. 4. Professor, Division of Endocrinology and Metabolism, Jichi Medical University Saitama Medical Center, Saitama, Japan.

Correspondence Address :
Dr. Hodaka Yamada,
Jichi Medical University Saitama Medical Center, 1-847 Amanuma-Cho, Omiya-Ku, 330-8503, Saitama, Japan.
E-mail: hyamada0510@jichi.ac.jp

Abstract

It is well known that fasting hypoglycaemia is common in insulinoma, but postprandial hypoglycaemia has also been reported. In almost all cases, the serum Immunoreactive Insulin (IRI) level is not suppressed. A 54-year-old Japanese woman experienced repeated temporary loss of consciousness simultaneously with hypoglycaemia. 5-hour on admission, she had repeated hypoglycaemia without suppression of insulin. A 5-hour Oral 75 gm Glucose Tolerance Test (5-hour OGTT) showed reactive hypoglycaemia. Her serum IRI level was suppressed. Enhanced pancreatic Magnetic Resonance Imaging (MRI) revealed a 10 mm sized tumour in the pancreas; we thus diagnosed her with insulinoma. A laparoscopic distal pancreatectomy was performed. The 5-hour OGTT was performed again post operatively. Her abnormal glucose tolerance remained, but her reactive hypoglycaemia improved. We conclude that reactive hypoglycaemia may occur in cases of insulinoma, and may be eliminated through operation. This case report has two important points. Firstly, the patientís reactive hypoglycaemia was demonstrated. Secondly, her improving reactive hypoglycaemic state was recorded in detail.

Keywords

Diabetes mellitus, Insulin, Pancreatic endocrine tumour

How to cite this article :

Shunsuke Funazaki, Hodaka Yamada, Yuko Matsumoto, Kazuo Hara. A CASE OF INSULINOMA WITH IMPROVED REACTIVE HYPOGLYCEMIA AFTER OPERATION. Journal of Clinical and Diagnostic Research [serial online] 2018 January [cited: 2018 Jan 18 ]; 12:OD04-OD06. Available from
http://jcdr.net/back_issues.asp?issn=0973-709x&year=2018&month=January&volume=12&issue=1&page=OD04-OD06&id=11030

DOI and Others

DOI: 10.7860/JCDR/2018/31218.11030

Date of Submission: Jun 29, 2017
Date of Peer Review: Aug 19, 2017
Date of Acceptance: Nov 24, 2017
Date of Publishing: Jan 01, 2018

FINANCIAL OR OTHER COMPETING INTERESTS: None.

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