Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Case report
Year : 2018 | Month : July | Volume : 12 | Issue : 7 | Page : QD08 - QD09

Childhood Onset Nephrotic Syndrome-A Journey Through Two Pregnancies

Shashikala K Bhat, Shashikiran Umakanth, Krupa Shah, Ashwini AP, Ravindra Prabhu

1. Professor and Unit Head, Department of Obstetrics and Gynaecology, Melaka Manipal Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India. 2. Professor and Head, Department of Medicine, Melaka Manipal Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India. 3. Associate Professor, Department of Obstetrics and Gynaecology, Melaka Manipal Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India. 4. Senior Resident, Department of Obstetrics and Gynaecology, Melaka Manipal Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India. 5. Professor and Head, Department of Nephrology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Correspondence Address :
Dr. Shashikiran Umakanth,
Professor and Head, Department of Medicine, Dr. TMA Pai Hospital, Udupi Melaka Manipal Medical College,
Manipal Academy of Higher Education,
Manipal, Karnataka, India.
E-mail: shashikiranu@gmail.com

Abstract

Nephrotic Syndrome (NS), a unique renal disease complex associated with heavy proteinuria (protein excretion >3.5 gm/day), hypoalbuminemia (<30 gm/L) and peripheral oedema. It is a rare entity in pregnancy, with an incidence of about 0.012-0.025%. There have been very few reports of pregnancy with co-existing NS. We hereby report a case of steroid sensitive childhood onset NS, due to minimal change disease and her course through two pregnancies. While she had a relapse of NS during her first pregnancy, she sailed through her second pregnancy without relapse. Women with NS can have a good maternal and perinatal outcome with multidisciplinary approach. Pregnancy does not always worsen the existing NS by causing a relapse or disease progression.

Keywords

Hypertension, Pregnancy, Proteinuria, Renal disease, Steroids

How to cite this article :

Shashikala K Bhat, Shashikiran Umakanth, Krupa Shah, Ashwini AP, Ravindra Prabhu. CHILDHOOD ONSET NEPHROTIC SYNDROME-A JOURNEY THROUGH TWO PREGNANCIES. Journal of Clinical and Diagnostic Research [serial online] 2018 July [cited: 2018 Jul 18 ]; 12:QD08-QD09. Available from
http://jcdr.net/back_issues.asp?issn=0973-709x&year=2018&month=July&volume=12&issue=7&page=QD08-QD09&id=11836

DOI and Others

DOI: 10.7860/JCDR/2018/36044.11836

Date of Submission: Feb 18, 2018
Date of Peer Review: Apr 23, 2018
Date of Acceptance: May 11, 2018
Date of Publishing: Jul 01, 2018

FINANCIAL OR OTHER COMPETING INTERESTS: NONE.

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