Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Case report
Year : 2018 | Month : March | Volume : 12 | Issue : 3 | Page : OD03 - OD05

A Rare Case of Amphotericin B Resistant Cryptococcal Meningitis in a HIV Non-reactive Immunocompetent Patient

Pulin Kumar Gupta, Subodh Kumar Mahto, Brinder Mohan Singh Lamba, Mahinder Pal Singh Chawla, Ankita Sheoran

1. Professor, Department of Medicine, DR. RML Hospital and PGIMER, New Delhi, India. 2. Senior Resident, Department of Medicine, DR. RML Hospital and PGIMER, New Delhi, India. 3. Professor, Department of Medicine, DR. RML Hospital and PGIMER, New Delhi, India. 4. Professor, Department of Medicine, DR. RML Hospital and PGIMER, New Delhi, India. 5. Post Graduate, Department of Medicine, DR. RML Hospital and PGIMER, New Delhi, India.

Correspondence Address :
Dr. Subodh Kumar Mahto,
Senior Resident, Medicine Department, OPD Block, DR. RML Hospital, New Delhi-110001, India.
E-mail: drsubodhkr05@gmail.com

Abstract

Cryptococcus meningitis is the most common opportunistic fungal infection in immunocompromised individuals and rarely occurs in HIV non-reactive people. Fever, headache, altered sensorium and neck stiffness are the usual presenting features of meningitis and common causative agents are of viral, mycobacterial and mostly bacterial origin in an immunocompetent host. However, fungal infection should be considered amongst the differentials. Knowledge of geographical distribution and a high degree of clinical suspicion are important for an early diagnosis, institution of early treatment and ultimately preventing lethal complications. We hereby report a case of amphotericin B resistant cryptococcal meningitis in a HIV non-reactive immunocompetent individual.

Keywords

Brain, Fungal infection, Glasgow coma scale, Obstructive hydrocephalus, Pleocytosis

How to cite this article :

Pulin Kumar Gupta, Subodh Kumar Mahto, Brinder Mohan Singh Lamba, Mahinder Pal Singh Chawla, Ankita Sheoran. A RARE CASE OF AMPHOTERICIN B RESISTANT CRYPTOCOCCAL MENINGITIS IN A HIV NON-REACTIVE IMMUNOCOMPETENT PATIENT. Journal of Clinical and Diagnostic Research [serial online] 2018 March [cited: 2018 Jun 22 ]; 12:OD03-OD05. Available from
http://jcdr.net/back_issues.asp?issn=0973-709x&year=2018&month=March&volume=12&issue=3&page=OD03-OD05&id=11238

DOI and Others

DOI: 10.7860/JCDR/2018/32555.11238

Date of Submission: Sep 13, 2017
Date of Peer Review: Oct 16, 2017
Date of Acceptance: Dec 6, 2017
Date of Publishing: Mar 01, 2018

FINANCIAL OR OTHER COMPETING INTERESTS: As declared above.

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