A Rare Case of Amphotericin B Resistant Cryptococcal Meningitis in a HIV Non-reactive Immunocompetent PatientCorrespondence Address :
Dr. Subodh Kumar Mahto,
Senior Resident, Medicine Department, OPD Block, DR. RML Hospital, New Delhi-110001, India.
Cryptococcus meningitis is the most common opportunistic fungal infection in immunocompromised individuals and rarely occurs in HIV non-reactive people. Fever, headache, altered sensorium and neck stiffness are the usual presenting features of meningitis and common causative agents are of viral, mycobacterial and mostly bacterial origin in an immunocompetent host. However, fungal infection should be considered amongst the differentials. Knowledge of geographical distribution and a high degree of clinical suspicion are important for an early diagnosis, institution of early treatment and ultimately preventing lethal complications. We hereby report a case of amphotericin B resistant cryptococcal meningitis in a HIV non-reactive immunocompetent individual.
Brain, Fungal infection, Glasgow coma scale, Obstructive hydrocephalus, Pleocytosis
Pulin Kumar Gupta, Subodh Kumar Mahto, Brinder Mohan Singh Lamba, Mahinder Pal Singh Chawla, Ankita Sheoran. A RARE CASE OF AMPHOTERICIN B RESISTANT CRYPTOCOCCAL MENINGITIS IN A HIV NON-REACTIVE IMMUNOCOMPETENT PATIENT. Journal of Clinical and Diagnostic Research [serial online] 2018 March [cited: 2018 Mar 18 ]; 12:OD03-OD05. Available from
Date of Submission: Sep 13, 2017
Date of Peer Review: Oct 16, 2017
Date of Acceptance: Dec 6, 2017
Date of Publishing: Mar 01, 2018
FINANCIAL OR OTHER COMPETING INTERESTS: As declared above.
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