Chromobacterium violaceum Related Urinary Tract Infection: A Case Report
DD01-DD02
Correspondence
Dr. Jharna Mandal,
Professor, Department of Microbiology, JIPMER, Puducherry-605006, India.
E-mail: drjharna@gmail.com
Chromobacterium violaceum (C. violaceum) is a motile, gram-negative bacillus found in water and moist soil. Infections due to C. violaceum are uncommon but have a significant mortality rate (upto 80%) due to their tendency for haematogenous dissemination resulting in sepsis. The organism has been reported to cause skin and soft tissue infections, diarrhoea, bacteremia, and visceral abscess; Urinary Tract Infection (UTI) is rarely seen. Here, a 41-year-old male diabetic who presented with fever, altered sensorium and burning micturition caused by C.violaceum is presented. Initial investigations revealed an increased Random Blood Sugar (RBS) level, high anion gap metabolic acidosis with normal renal and liver function (except for hypoalbuminemia). Diabetic ketoacidosis, probable meningitis and urosepsis were considered as differential diagnosis. On culture of a urine sample, C. violaceum was isolated, which was susceptible to all the antibiotics tested except amikacin. Blood culture was reported as sterile. The patient was successfully treated with a susceptible antibiotic (ciprofloxacin), and repeat culture of the urine was also sterile. Early diagnosis and adequate treatment are necessary to reduce the risk of progression to fatal infection.