Assessment of Osteoporotic Alterations in Brazilian Postmenopausal Women: A Retrospective Study ZC34-ZC37
Dr. Isabela Goulart Gil Choi,
2227 Lineu Prestes Avenue, Zip Code: 05508-000, SÃ£o Paulo, Brazil.
Introduction: Peripheral Dual X-Ray Absorptiometry (DXA) has been recognized as convenient to assess Bone Mass Density (BMD) and fracture risk. Nevertheless, DXA is not largely available mainly in developing countries and early diagnosis in high-risk groups become impaired as the screening is not usually performed. Meanwhile, panoramic radiographs are commonly used in routine dentistry practice and mandibular cortical bone may reflect changes in bony architecture from other sites of skeleton.
Aim: To assess BMD by peripheral DXA and osteoporotic alterations in mandibular cortical bone by panoramic radiographs using Mandibular Cortical Index (MCI) in Brazilian women, according to age ranges.
Materials and Methods: The T-scores of peripheral DXA were assessed in 252 female patients considering eight age ranges. The relationship between age and T-scores were performed by logistic regression. In addition, non-parametric correlations between MCI and peripheral DXA (pDXA) results were carried out with Spearmanâ€™s test at a level of significance of 5%.
Results: The age-related bone loss showed to be less significant at distal site and markedly more evident in proximal sites. The higher T-score values at proximal radius was observed in 25-39 age range group; in 40-44 age range group for distal forearm and in 45-49 age range group at the proximal R+U site. For MCI test, interobserver and intraobserver reproducibility were confirmed for MCI categorical measurements (kappa=0.81, p=0.01). It was found different inverse correlations between MCI and the different forearm sites: stronger for proximal sites and weaker for the distal site.
Conclusion: Within the limitations of this study, we concluded that age-related bone loss is more evident in proximal forearm than in the distal forearm and MCI can express better inverse correlation with proximal forearm.