Diffuse Nodular Pseudoangiomatous Stromal Hyperplasia causing Bilateral Gigantomastia with Follow-up of 2 Year Post Reduction Mammoplasty TD06-TD08
Dr. Teena Sleeba,
1401, Oceanus Maple, Edapally, Kochi-682024, Kerala, India.
Pseudoangiomatous Stromal Hyperplasia (PASH) is an uncommon benign mesenchymal tumour of the breast with no known potential for malignancy. PASH is often detected incidentally or in a background of other breast pathologies. Being hormonally driven, these are most commonly seen in women in the reproductive age group. The size of the PASH varies with small microscopic PASH being much more common than the tumourous or infiltrative varieties. It is uncommon to see PASH presenting as diffuse nodular masses replacing the entire glandular parenchyma symmetrically on both sides. We report a case of a 31-year-old non lactating lady, in whom PASH caused bilateral symmetrical gigantomastia. As PASH has been shown to have a high chance of recurrence, review of literature revealed that most women with PASH-associated gigantomastia undergo mastectomy rather than reduction mammoplasty. We followed up our patient for two years post-reduction mammoplasty with no increase in dimensions of existing lesions or development of new lesions both clinically and on imaging.