
Phytotherapeutics for Wound Healing: A Systematic Review on Effectiveness of Indian Herbal Extracts in Rat Models
JE01-JE05
Correspondence
Nitesh Laxman Shambharkar,
Shivam Vatika Mopka, Bilaspur-495006, Chhattisgarh, India.
E-mail: dr.niteshshambharkar70@gmail.com
Wound healing is a multifaceted process that encompasses a coordinated set of chemical and cellular events aimed at restoring the integrity of the skin and underlying tissues. Globally, many individuals turn to medicinal plants as an alternative therapy for this purpose. The present review focuses on evaluating the in-vivo wound healing activity of herbal plant extracts native to India, comparing them with povidone-iodine. Plant extracts show potential as promising wound healing agents due to their rich active compounds, wide availability and low risk of side-effects. Data were gathered from various sources, including scientific databases such as Google Scholar, PubMed and ScienceDirect. Keywords such as “wound healing,” “animal studies,” “herbal,” “Wistar albino rats,” “India,” and “Ayurvedic” were used to identify relevant articles, which were then analysed. The present review compiles data from articles published over the past 14 years on the in-vivo wound healing potential of medicinal plants in rats, with povidone-iodine consistently used as a reference in these studies. The findings highlight the potential of medicinal plants to contribute to drug discovery as effective wound healers, which may lead to the development of new, safe drug molecules. Further research is required, including novel formulations and targeted drug delivery systems, alongside clinical trials, to scientifically validate these findings and transition them from the laboratory to industry for broader societal benefit.