Original article / research
Association of Pancreatic Pseudocysts and Walled-off Necrosis with Clinical Characteristics and Management in Acute Pancreatitis: A Prospective Analytical Study
TC06-TC09
Correspondence
Dr. Mulupuru Krishna Sowmya,
64-9-17, Chennupati Ramakotaiah Street, Patamatalanka, Vijayawada, Andhra Pradesh, India.
E-mail: sowmyamulpuri19@gmail.com
Introduction: Acute Pancreatitis (AP) is a common inflammatory condition with a clinical spectrum ranging from mild self-limiting disease to severe necrotising pancreatitis associated with significant morbidity and mortality. Early assessment of disease severity is essential for appropriate management and prognostication. Contrast-Enhanced Computed Tomography (CECT) plays a crucial role in evaluating pancreatic necrosis, peripancreatic changes, and local complications.
Aim: To evaluate the association of pancreatic pseudocysts and Walled-off Necrosis (WON) with clinical characteristics and management in patients with AP using CECT.
Materials and Methods: A hospital-based prospective analytical study was conducted in the Department of Radiology, Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation, Andhra Pradesh, India, from April 2024 to January 2026. A total of 50 consecutive patients with AP who underwent CECT were included. Pancreatic and peripancreatic fluid collections were classified according to the 2012 Revised Atlanta Classification. Demographic, and outcome data were collected, and associations between the type of fluid collection and clinical characteristics, management, hospital stay, organ failure, and mortality were analysed using appropriate statistical tests.
Results: Among 50 patients with AP, 41 (82%) were males, and the 41-50 years age group constituted the largest proportion (32%). Alcohol was the most common aetiology (58%). Pseudocyst was the most frequent fluid collection (58%), while WON was observed in 42% of patients. Moderate and severe pancreatitis was present in 52% and 48% of patients, respectively. A significant association was observed between the type of pancreatic fluid collection and management approach (p-value=0.0449). However, no significant association was found between the type of fluid collection and hospital stay, organ failure, mortality, Modified Computed Tomography Severity Index (MCTSI) score, infection, gender, or aetiology (p-value >0.05).
Conclusion: CECT-based assessment using the Revised Atlanta Classification demonstrated a significant association between the type of pancreatic fluid collection and the management approach in the current study.