Applications of Arterial Spin Labelling Sequence in Neuroimaging, Case Depictions with Examples: A Case Series
Published: April 1, 2023 | DOI: https://doi.org/10.7860/JCDR/2023/62962.17760
Chandrasekhar Patil, Arun Kumar, KS Prashanth Kumar, Vasudha Battula, Sai Kotamraju
1. Assistant Professor, Department of Radiology, Malla Reddy Medical College for Women, Kukatpally, Hyderabad, Telangana, India.
2. Assistant Professor, Department of Radiology, Subbaiah Institute of Medical Sciences, Shimoga, Karnataka, India.
3. Professor, Department of Radiology, Malla Reddy Medical College for Women, Hyderabad, Telangana, India.
4. Senior Resident, Department of Paediatrics, Malla Reddy Medical College for Women, Hyderabad, Telangana, India.
5. Senior Resident, Department of Radiology, Malla Reddy Medical College for Women, Hyderabad, Telangana, India.
Correspondence
Dr. Chandrasekhar Patil,
Assistant Professor, Department of Radiology, Malla Reddy Medical College for Women, Kukatpally, Hyderabad-500055, Telangana, India.
E-mail: drchandruhbli@gmail.com
Since many neurological diseases are associated with altered regional cerebral flow, Arterial Spin Labelling (ASL) image being a non invasive non contrast sequence, is increasingly being used and incorporated in routine protocols as an adjuvant sequence to study the regional alterations in cerebral perfusion or Cerebral Blood Flow (CBF). It demonstrates increased or decreased regional CBF in various brain pathologies reliably without the use of intravenous contrast material. In this case series (seven cases), ASL is increased (increased CBF) in cases of high-grade tumour, highly cellular tumours, encephalitis, tumour recurrence, acute phase of Posterior Reversible Encephalopathy Syndrome (PRES), and decreased in cerebral infarct, periinfarct ischaemic penumbra, thereby making an effort to emphasise the significance and utilisation of ASL in adjunct to the other routine Magnetic Resonance Imaging (MRI) sequences.
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