Primary Myelofibrosis with Mesenteric Extramedullary HaematopoiesisCorrespondence Address :
Dr. Saurabh Kumar,
Assistant Professor, Department of Radiology Institute of Liver and Biliary Sciences (ILBS)
D-1, Vasant kunj, New Delhi, Delhi, India.
Primary myelofibrosis or chronic idiopathic myelofibrosis is a myeloproliferative neoplasm characterized by proliferation of abnormal haematopoietic stem cells in bone marrow resulting in replacement of marrow with fibrotic scar tissue. Extramedullary Haematopoiesis (EMH) as a compensatory phenomenon in myelofibrosis can lead to hepatosplenomegaly with diffuse organ infiltration or focal deposits. Peritoneal involvement of EMH is rare and can present with peritoneal or serosal implants which can mimic malignancy. We present a case of diffuse peritoneal /mesenteric extramedullary haematopoiesis with hepatosplenomegaly as an initial presentation in patient of idiopathic myelofibrosis.
Megakaryocytes, Myeloproliferative neoplasm, Osteosclerosis
Saurabh Kumar, Shaloo shaloo, Juhi Chawla, Subha ashok, Shalini Thapar Laroia. PRIMARY MYELOFIBROSIS WITH MESENTERIC
EXTRAMEDULLARY HAEMATOPOIESIS. Journal of Clinical and Diagnostic Research [serial online] 2018 December [cited: 2018 Dec 14 ]; 12:TD01-TD02. Available from
Date of Submission: May 24, 2018
Date of Peer Review: Jul 13, 2018
Date of Acceptance: Aug 16, 2018
Date of Publishing: Dec 01, 2018
Financial OR OTHER COMPETING INTERESTS: None.
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