Metastatic Renal Cell Carcinoma in Nasopharynx-A Paradox: Case Report and Review of LiteratureCorrespondence Address :
Dr. Faheema Hasan,
Final year Postgraduate Resident, Department of Pathology, Moti Lal Nehru Medical College, Allahabad-211002,
Uttar Pradesh, India.
Metastatic renal cell carcinoma of the head and neck is extremely rare. Metastasis to the nasopharynx is extremely unusual and can be misdiagnosed as primary of the specific site hindering further management. The present case report of an 82-year-old male presenting with epistaxis was found to have a nasopharyngeal mass on radiology. Microscopic evaluation of the nasopharyngeal mass revealed a highly vascular clear cell tumour with cells arranged in alveolar and trabecular pattern. Immunohistochemical assessment revealed positive PAX 8, CD10 and vimentin which are highly specific for metastatic renal cell carcinoma. Retrospective computed tomography scan revealed a renal mass; however, the patient succumbed before any biopsy could be performed.
Clear cell tumour, Epistaxis, Immunohistochemistry
Kachnar Varma, Faheema Hasan, Vatsala Misra, PA Singh. METASTATIC RENAL CELL CARCINOMA IN
NASOPHARYNX-A PARADOX: CASE REPORT
AND REVIEW OF LITERATURE. Journal of Clinical and Diagnostic Research [serial online] 2018 July [cited: 2018 Oct 19 ]; 12:ED01-ED03. Available from
Date of Submission: Jul 18, 2017
Date of Peer Review: Sep 08, 2017
Date of Acceptance: Mar 28, 2018
Date of Publishing: Jul 01, 2018
FINANCIAL OR OTHER COMPETING INTERESTS: None.
- Emerging Sources Citation Index (Web of Science, thomsonreuters)
- Index Copernicus ICV 2016: 132.37
- Academic Search Complete Database
- Directory of Open Access Journals (DOAJ)
- Embase & EMbiology
- Google Scholar
- HINARI Access to Research in Health Programme
- Indian Science Abstracts (ISA)
- Journal seek Database
- Popline (reproductive health literature)