Effect of Vitamin C Supplementation on Anthropometric Measurements, Lipid Profile and Atherogenic Indices in Obese and Non Obese IndividualsCorrespondence Address :
Mr. Ganesh H Ghanwat,
Tutor, Department of Biochemistry, Krishna Institute of Medical Sciences, Karad-415539, Maharashtra, India.
Introduction: The prevalence of obesity is increasing day by day in India. Since obesity is associated with occurrence of oxidative stress, antioxidants can be used to treat the obesity and overcome associated complications.
Aim: The present study was aimed to analyse the effect of vitamin C intake on anthropometric measurements, lipid profile and atherogenic indices in obese and non obese individuals and to find out the correlation between study variables.
Materials and Methods: Total 39 male individuals; 20 obese and 19 non obese were involved in this study and they received 1500 mg vitamin C daily for three months. After 12-14 hours of overnight fast, Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), Body Mass Index (BMI), Body Adiposity Index (BAI), Waist Circumference (WC), Hip Circumference (HC), Waist to Hip Ratio (WHR), Waist to Height Ratio (WHtR), serum lipid profile and atherogenic indices were measured, in obese and non obese individuals, at the initiation of the work and after consumption of vitamin C, by the end of three months. Total study subjects were divided into two groups for convenience and called on two consecutive days. Data were analysed by using two tailed Student’s t-test.
Results: Present study reported significant decrease in SBP, BMI, BAI, WC, HC, WHR, WHtR, in both obese and non obese individuals and significant decrease in TC, TG, VLDL-C but no alteration in Low Density Lipoprotein-Cholesterol (LDL-C) and HDL-C in obese individuals. Similarly, no significant changes were observed in lipid profile of non obese and atherogenic indices of both obese and non obese subjects, after the consumption of vitamin C.
Conclusion: Present study concludes that, daily intake of 1500 mg of vitamin C has positive lowering effect on anthropometric measurements and lipid profile however it is not significantly effective in lowering atherogenic indices in a short span of three months. Long term administration of vitamin C may be helpful for dieticians and clinicians in advising high intake of vitamin C through the diet like amla, guava, citrus fruits etc., in controlling obesity and related disorders.
Atherogenic index, Body mass index, Obesity, Plasma, Total cholesterol, Triglycerides
Ganesh H Ghanwat, Ajit V Sontakke. EFFECT OF VITAMIN C SUPPLEMENTATION ON ANTHROPOMETRIC MEASUREMENTS, LIPID PROFILE AND ATHEROGENIC INDICES IN OBESE AND NON OBESE INDIVIDUALS. Journal of Clinical and Diagnostic Research [serial online] 2018 October [cited: 2018 Sep 24 ]; 12:BC11-BC17. Available from
Date of Submission: Apr 23, 2018
Date of Peer Review: Jun 11, 2018
Date of Acceptance: Jul 30, 2018
Date of Publishing: Oct 01, 2018
FINANCIAL OR OTHER COMPETING INTERESTS: None.
- Emerging Sources Citation Index (Web of Science, thomsonreuters)
- Index Copernicus ICV 2016: 132.37
- Academic Search Complete Database
- Directory of Open Access Journals (DOAJ)
- Embase & EMbiology
- Google Scholar
- HINARI Access to Research in Health Programme
- Indian Science Abstracts (ISA)
- Journal seek Database
- Popline (reproductive health literature)