Some Objectivity to the Ethical Aspects in Conduct of Clinical Research in Vulnerable PopulationCorrespondence Address :
ICMR National Institute of Medical Statistics, Ansari Nagar, New Delhi, India.
Vulnerable population is one of the important parts of our population which also need to be benefited from the results of clinical research. In view of their limited autonomy it may not be easy to conduct clinical research such as clinical trials in them because of ethical issues. When it is must to conduct clinical trial in this population, along with ethical considerations, some statistical and clinical research issues may also be addressed to give the objectivity to the decision of conducting trials in this population, which is not in a position to convey their acceptance of participating in the trial independently. The paper discusses the issues in vulnerable population through the concepts in clinical research and some objective ethical considerations before arriving at the decision of conducting a clinical trial.
Clinical trial, Effect size, Ethics
Atul Juneja, Tulsi Adhikari, M Vishnu Vardhana Rao. SOME OBJECTIVITY TO THE ETHICAL ASPECTS IN CONDUCT OF CLINICAL RESEARCH IN VULNERABLE POPULATION. Journal of Clinical and Diagnostic Research [serial online] 2019 February [cited: 2019 Apr 25 ]; 13:YM01-YM02. Available from
Date of Submission: Aug 24, 2018
Date of Peer Review: Oct 11, 2018
Date of Acceptance: Dec 05, 2018
Date of Publishing: Feb 01, 2019
FINANCIAL OR OTHER COMPETING INTERESTS: None.
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