Insulinoma: A Diagnostic Challenge!Correspondence Address :
Dr. Janet Prameela D’Souza,
Assistant Professor, Manipal College of Nursing, Manipal Academy of Higher Education,
Madhava Nagar, Manipal-576104, Karnataka, India.
Insulinoma is a common tumour arising from islets of Langerhans. Patients with insulinomas present with neuroglycopenic symptoms such as repeated episodes of headache, blurred vision, diplopia and lethargy especially with fasting or exercise. Seizures, coma and permanent brain damage results from severe hypoglycaemia. The present report is of a female who got admitted with the chief complaints of swaying on to one side since one month and slurring of speech, seizures and becoming drowsy for four days. Her laboratory values indicated repeated episodes of hypoglycaemia in spite of repeated administration of intravenous dextrose. A CT scan of pancreas revealed insulinoma and was treated by surgical resection. After surgery, patient’s symptoms subsided and she recovered well. The clinical manifestations of insulinoma mimic features of diabetes mellitus and neuropsychiatric disorders, hence a thorough investigation needs to be done to confirm the diagnosis.
Hypoglycaemia, Neuroglycopenic symptoms, Pancreatic neoplasm, Pancreatic tumour, Resection
Janet Prameela D’Souza, Gabriel Sunil Rodrigues, Leena Sequira, Amanda Varghese. INSULINOMA: A DIAGNOSTIC CHALLENGE!. Journal of Clinical and Diagnostic Research [serial online] 2019 January [cited: 2019 Jan 20 ]; 13:LD01-LD02. Available from
Date of Submission: Aug 11, 2018
Date of Peer Review: Sep 14, 2018
Date of Acceptance: Oct 29, 2018
Date of Publishing: Jan 01, 2019
FINANCIAL OR OTHER COMPETING INTERESTS: None.
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