Systemic Thrombolytic Therapy for Pulmonary Embolism in Early Postoperative Period Following Laparoscopic Vaginal HysterectomyCorrespondence Address :
Dr. Shaik Gulam Osmani,
C1-8, Kasturba Medical College Quarters, Near Jyothi Circle, Mangalore-575001, Karnataka, India.
A 51-year-old female underwent a laparoscopic-assisted vaginal hysterectomy for fibroid uterus. After an uneventful procedure, the patient developed symptoms of Pulmonary Thromboembolism (PTE). The PTE was managed with, systemic thrombolysis using tissue plasminogen activator (Tenecteplase), appropriate support of inotropes and anticoagulants. While there is less incidence of PTE in laparoscopic procedures, in particular, in gynaecology, there is a definite risk even in a patient with low-risk factors, which has been highlighted. Prompt diagnosis, aggressive therapy and adequate haemodynamic support go a long way to reduce mortality and morbidity from this life-threatening complication.
Anticoagulants, Fibroid uterus, Tenecteplase, Venous thrombosis
BV Sunil, Shaik Gulam Osmani, S Neeta, Sarath Venugopal, Hariharan Kannan. SYSTEMIC THROMBOLYTIC THERAPY FOR PULMONARY EMBOLISM IN EARLY POSTOPERATIVE PERIOD FOLLOWING LAPAROSCOPIC VAGINAL HYSTERECTOMY. Journal of Clinical and Diagnostic Research [serial online] 2019 January [cited: 2019 Jan 23 ]; 13:QD01-QD02. Available from
Date of Submission: Sep 17, 2018
Date of Peer Review: Oct 27, 2018
Date of Acceptance: Nov 10, 2018
Date of Publishing: Jan 01, 2019
FINANCIAL OR OTHER COMPETING INTERESTS: None.
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