Study of Latency Interval of Moro Reflex in Full-term Newborns with Hypoxic Ischaemic EncephalopathyCorrespondence Address :
Dr. Sunil Kumar Rao,
Associate Professor, Department of Paediatrics, IMS, BHU, Varanasi-221005, Uttar Pradesh, India.
Introduction: Neurological morbidities are the earliest presentation of hypoxic insult in newborns. Parents seek medical advice when they notice abnormal posture or abnormal movements or persistent cry or delayed milestones. By that time pathophysiology would have set in and would have led to irreversible changes in brain which subsequently manifests in developing period of brain or later. Early recognition of asphyxiated newborns and their timely referral has better neurological outcome.
Aim: To describe Moro’s response in newborns with Hypoxic Ischaemic Encephalopathy (HIE) by using Ordinal scale.
Materials and Methods: This was a prospective cross-sectional study conducted in a tertiary care hospital. Inclusion criteria were full term newborns with HIE. Recruited newborns were classified in different grades of HIE after initial stabilisation, two investigators were present in examination room, one investigator examined the Moro’s response while the baby was alert, active and moving the limbs by using head drop method. Whole event was recorded by second investigator and third investigator was calculating the latency interval of Moro’s response by using stopwatch with accuracy of 1/100 of a second from video recording separately. Moro’s response was assessed by ordinal scale.
Results: Final analysis was done on 104 newborns, out of which 18 had absent reflex, 17 had long latency interval, 19 had normal latency interval and 50 newborns had short latency interval. Long latency of Moro response had sensitivity of 45.95%, with 50.8% of accuracy to screen deviant Moro’s response in HIE.
Conclusion: Long latency interval of Moro response could be a valuable clinical sign to screen for neurological impairment in HIE.
Asphyxia, Deviant moro response, Long latency, Ordinal scale
Kamal Kishore Sagaria, Sunil Kumar Rao. STUDY OF LATENCY INTERVAL OF MORO REFLEX IN FULL-TERM NEWBORNS WITH HYPOXIC ISCHAEMIC ENCEPHALOPATHY. Journal of Clinical and Diagnostic Research [serial online] 2019 January [cited: 2019 Jan 22 ]; 13:SC07-SC09. Available from
Date of Submission: Jul 30, 2018
Date of Peer Review: Aug 20, 2018
Date of Acceptance: Dec 12, 2018
Date of Publishing: Jan 01, 2019
FINANCIAL OR OTHER COMPETING INTERESTS: None.
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