Ankylosing Spondylitis Causing Obstructive Lung Disease and Tricuspid Insufficiency: A Case ReportCorrespondence Address :
H No. 440-A, Suraksha Colony, Saili Road, Pathankot, Punjab, India.
Ankylosing Spondylitis (AS) is a chronic progressive inflammatory spondyloarthropathy typically involving the axial skeleton, especially the sacroiliac joints and spine. Genetic predisposition in AS leads to its common association with certain extra-articular diseases-anterior uveitis (25-30%), psoriasis (10%) and inflammatory bowel diseases (50%). Cardiorespiratory involvement in AS is rare and is usually present in long standing disease as restrictive lung disease, conduction abnormalities or aortic insufficiency. Here, we present a case of unusual AS in a 32-year-old non-smoker male with a major involvement of peripheral joints along with spine and chronic obstructive lung disease with apical fibro-bullous cavity and right sided heart failure over a short duration of disease course. His condition was acutely stabilised with diuretics, anti-hypertensive drugs, anti-pyretics, antibiotics and oxygen inhalation followed by maintenance on Non-steroidal anti-inflammatory agents. Hence, in a patient of AS, a strong index of suspicion should be there for both usual and unusual extra-articular manifestations and a complete work-up would help in early diagnosis and treatment.
Axial spondyloarthritis, Cavitary lung disease, Obstructive lung disease, Restrictive lung disease, Right heart failure, Seronegative spondyloarthropathy
Amisha, Paras Malik, Monika Pathania, Vyas Kumar Rathaur. ANKYLOSING SPONDYLITIS CAUSING OBSTRUCTIVE LUNG DISEASE AND TRICUSPID INSUFFICIENCY: A CASE REPORT. Journal of Clinical and Diagnostic Research [serial online] 2019 June [cited: 2019 Jun 18 ]; 13:OD01-OD03. Available from
Date of Submission: Mar 24, 2019
Date of Peer Review: Apr 08, 2019
Date of Acceptance: Apr 22, 2019
Date of Publishing: Jun 01, 2019
FINANCIAL OR OTHER COMPETING INTERESTS: None.
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