Diffuse Tuberculous Cerebritis in Immunocompetent Hosts-An Uncommon EntityCorrespondence Address :
Dr. Animesh Das,
Neurology Resident, Department of Neurology, SGPGI, Lucknow-226014, Uttar Pradesh, India.
Central Nervous System (CNS) tuberculosis is a common disease in developing countries with varied presentation, the most common being tuberculous meningitis. Meningitis, in many cases leads to infection of the underlying cortex resulting in cerebritis, encephalitis or abscess formation. Tuberculous cerebritis has either been described as a focal entity in normal subjects or as a diffuse entity in immunocompromised hosts. We present here two cases of diffuse tuberculous cerebritis in immunocompetent patients. One had presented with left focal seizure with paraparesis while the other presented with non-localising features of raised intracranial pressure. Tubercular Polymerase Chain Reaction (PCR) was positive in Cerebrospinal Fluid (CSF) in the first patient while CSF picture was suggestive of tubercular meningitis in the second making him a possible case of tuberculosis. Both the patients improved significantly on anti-tubercular drugs.
Arachnoiditis, Central nervous system infection, Paraparesis, Tuberculosis
Animesh Das. DIFFUSE TUBERCULOUS CEREBRITIS IN IMMUNOCOMPETENT HOSTS-AN UNCOMMON ENTITY. Journal of Clinical and Diagnostic Research [serial online] 2019 March [cited: 2019 Feb 18 ]; 13:OD01-OD03. Available from
Date of Submission: Nov 23, 2018
Date of Peer Review: Dec 13, 2018
Date of Acceptance: Dec 18, 2018
Date of Publishing: Mar 01, 2019
FINANCIAL OR OTHER COMPETING INTERESTS: None.
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