Ovarian Neoplasms: Clinicopathological Spectrum in Tribal Rajasthan, IndiaCorrespondence Address :
AS4, Doctor's Quarters, Geetanjali Medical College Udaipur, Rajasthan, India.
Introduction: Ovarian neoplasms have increased in incidence in leading sites of cancer in five old population based cancer registries on comparing first ten and last ten years data. All three germ layers are afflicted in process of ovarian neoplasm-ceolomic epithelium, germ cell and sex chord/stromal cells. Due to this, ovarian masses are spread widely over all age groups. However, a correct pathological diagnosis goes a long way in management of the disease and consequent benefit to patient.
Aim: To assess the histopathological pattern, age, laterality and distribution of ovarian tumours in a tertiary care centre of tribal part of Rajasthan.
Materials and Methods: Retrospective hospital based study wherein 157 ovarian specimens received in Department of Pathology of Geetanjali Medical College and Hospital, Udaipur, Rajasthan over a period of three years were studied after obtaining permission of ethical committee. Details such as age, signs and symptoms, laterality were retrieved from patient file. Only benign, borderline or malignant ovarian neoplasm specimens removed surgically were included. Physiological cysts were excluded. Descriptive statistics were used and results were expressed as percentages.
Results: Out of 157 ovarian neoplasms, 42 (26.75%) were from hysterectomy specimen, 44 (28.02%) from planned cystectomy for mass, 71 (45.22%) from cytoreductive surgery or tissue obtained from Exploratory Laparotomy. A 63.06%, 33.76% and 3.18% of neoplasms were benign, malignant and borderline, respectively. Extremes of age lied between 14 to 84 years. Mean age for benign, malignant and borderline tumours respectively was 38.60 years (SD 15.21), 47.79 years (SD 14.53) and 38.4 years (SD 14.04) respectively. Unilateral tumours were clearly in abundance with 85.35%. Right-sided tumours were more (49.04%). Surface Epithelial Tumours (SET’s), Germ Cell Tumour (GCT’s) and Sex Chord Stromal Tumours (SCSCT’s) were 59.24 %, 34.39% and 6.37%, respectively. Out of 10 cases, 60% were malignant (Granulosa cell tumour). No metastatic tumour was seen during the study period.
Conclusion: To effectively reverse the trend in a developing country like India each and every gynaecologist should be aware and well versed with histo-morphological pattern of ovarian neoplasms specific to a region.
Age, Benign, Borderline, Germ cell tumour, Malignant, Mass ovary, Sex chord stromal tumour
Date of Submission: Dec 30, 2020
Date of Peer Review: Jan 06, 2020
Date of Acceptance: May 27, 2021
Date of Publishing: Jul 01, 2021
• Financial or Other Competing Interests: None
• Was Ethics Committee Approval obtained for this study? Yes
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. NA
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ETYMOLOGY: Author Origin
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- Popline (reproductive health literature)