Rapidly Growing Mycobacterium in Postsurgical Wounds: A Systematic Review and Meta-analysis
Correspondence Address :
Shubhangi Mhaske,
Professor and Head, Department of Oral Pathology, People’s College of Dental
Science and Research Centre, Bhopal, Madhya Pradesh, India.
E-mail: mhaske_shubhangi@yahoo.com
Introduction: Rapidly Growing Mycobacteria (RGM) are extensively found in nature and is isolated as an environmental saprophyte from water sources and soil. The incidence of these opportunistic pathogens has increased in the recent years as nosocomial outbreaks, with an exaggerated outcome of morbidity and resistant antibiotic intervention.
Aim: To assess the occurrence of rapidly growing mycobacteria in postsurgical wounds.
Materials and Methods: Literature search in PubMed, Google Scholar and Scopus of published articles in English language from March 2010 to December 2020 were anlaysed for the predetermined outcomes. Keywords used for the literature search were "atypical mycobacteria"; "non tuberculous mycobacteria"; "rapidly progressing mycobacteria"; "RGM"; "postsurgical wounds"; "surgical site infection"; "wound site"; "port hole infections". A total of 10 studies adhering to Preferred Reporting Items for Systematic Reviews and MetaAnalyses (PRISMA) guidelines were included for statistical analysis. OpenMeta-Analyst software was used.
Results: A prevalence of 56.4% (95% CI: 33.0; 79.8) was noted in 592 patients evaluated postsurgically. The articles included were of fair quality when assessed on Ottawa scale. M.Chelonae, M.Abscessus, M.fortuitum and M.massiliense were the most commonly isolated organisms. Clarithromycin, Amikacin, Ciprofloxacin, Imepenem and Linezolids were administered as antibiotic intervention.
Conclusion: Considering the higher prevalence of RGM infection (56.40%), every surgeon must consider the possibility of this opportunistic infection. It is vital
Antibiotics, Non tuberculous mycobacteria, Occurrence, Surgical infection
DOI: 10.7860/JCDR/2021/52618.15744
Date of Submission: Sep 28, 2021
Date of Peer Review: Oct 20, 2021
Date of Acceptance: Nov 08, 2021
Date of Publishing: Dec 01, 2021
AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was Ethics Committee Approval obtained for this study? No
• Was informed consent obtained from the subjects involved in the study? No
• For any images presented appropriate consent has been obtained from the subjects. No
PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Sep 29, 2021
• Manual Googling: Oct 08, 2021
• iThenticate Software: Nov 06, 2021 (17%)
ETYMOLOGY: Author Origin
- Emerging Sources Citation Index (Web of Science, thomsonreuters)
- Index Copernicus ICV 2017: 134.54
- Academic Search Complete Database
- Directory of Open Access Journals (DOAJ)
- Embase
- EBSCOhost
- Google Scholar
- HINARI Access to Research in Health Programme
- Indian Science Abstracts (ISA)
- Journal seek Database
- Popline (reproductive health literature)
- www.omnimedicalsearch.com