Moyamoya Syndrome with Recurrent Stroke in a Splenectomised Patient with Beta-Thalassaemia Major: A Case Report
Correspondence Address :
Vijetha Chanabasanavar,
Junior Resident, Department of Radiodiagnosis, Dr. D. Y. Patil Vidyapeeth Medical
College and Research Centre, Pimpri, Pune, Maharashtra, India.
E-mail: vijethachanabasanavar@gmail.com
Moyamoya Syndrome (MMS) is a progressive disease with typical angiographic ‘moyamoya’ alterations. Here, the authors discuss a case of 16-year-old male patient who developed MMS after being diagnosed with ß-thalassaemia major. This patient was detected with heterozygous mutations in the ß-globin gene and underwent splenectomy at the age of 12 years. Four years postsplenectomy he presented with paresis of the right upper limb. Magnetic Resonance Imaging (MRI) showed infarction and stenosis of the internal carotid artery with the collateral vessel’s formation. Recurrence of stroke and progression of the vasculopathy were seen. Till now, only a few cases of MMS have been linked to thalassaemia major.
Endothelial proliferation, Hypercoagulopathy, Splenectomy
DOI: 10.7860/JCDR/2021/51360.15811
Date of Submission: Jul 13, 2021
Date of Peer Review: Oct 25, 2021
Date of Acceptance: Nov 17, 2021
Date of Publishing: Dec 01, 2021
AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. Yes
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• Plagiarism X-checker: Jul 29, 2021
• Manual Googling: Nov 08, 2021
• iThenticate Software: Nov 16, 2021 (3%)
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