
Clinical Evaluation of Vajigandhadi taila matrabasti versus Sahacharadi taila matrabasti in the Management of Gridhrasi (Sciatica): A Study Protocol
Correspondence Address :
Dr. Anil Ambadas Bhawade,
PhD Scholar, Department of Panchakarma, Mahatma Gandhi Ayurved College Hospital and Research Centre, Salod (H), Datta Meghe Institute of Higher Education and Research (DMIHER) (Deemed to be University), Salod, Wardha-442004, Maharashtra, India.
E-mail: anilbhawade@gmail.com
Introduction: In Ayurveda, Basti, or medicated enema, is recognised as a crucial component of Panchakarma, constituting half of the therapeutic approach. Matra Basti, a specific form of Basti Karma, is particularly effective in addressing disorders related to the nervous system, neuromuscular conditions and nutritional imbalances. Gridhrasi, commonly known as sciatica, is characterised by pain that extends from the lower back to the legs. These conditions frequently develop due to a variety of factors, such as poor sitting posture, excessive physical strain and a sedentary lifestyle.
Need of the study: In Ayurvedic practice, different medicated oils are prescribed based on the patient and the specific disease condition. Both Vajigandhadi oil and Sahacharadi oil are Ayurvedic formulations recommended for the treatment of Gridhrasi (sciatica) through per rectal administration. However, the comparative efficacy of these two oils in alleviating sciatic pain remains unclear. To address this knowledge gap, the present study will be conducted.
Aim: To compare the efficacy of Vajigandhadi taila matrabasti (a form of unctuous enema) with Sahacharadi taila matrabasti (another form of unctuous enema) for the management of Gridhrasi (sciatica).
Materials and Methods: A randomised controlled clinical trial will be conducted at MG Ayurved College, Hospital and Research Centre located in Salod (H), District Wardha, Maharashtra, India, from December 2022 to December 2025. In this study, a total of 80 participants will be randomly assigned to two groups, each consisting of 40 patients. Participants in group A will receive a Vajigandhadi taila matrabasti (a type of unctuous enema) at a dosage of 72 mL, administered rectally after meals for 14 days. Conversely, group-B will receive a Sahacharadi taila matrabasti (an unctuous enema) at the same dosage and administration schedule. Parameters will be assessed on the initial day, the 14th day and again after 30 days for follow-up purposes. Statistical analysis will be conducted using R (version 4.3.2) software. Objective parameters will be analysed using Independent t-tests, while subjective parameters will be analysed using Chi-square tests. Results will be presented as mean and standard deviation, with statistical significance at p-value <0.05.
Basti, Pain, Rectal enema, Sciatic nerve
DOI: 10.7860/JCDR/2025/68788.21066
Date of Submission: Nov 29, 2023
Date of Peer Review: Jan 13, 2024
Date of Acceptance: Mar 03, 2025
Date of Publishing: Jun 01, 2025
AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was Ethics Committee Approval obtained for this study? Yes
• Was informed consent obtained from the subjects involved in the study? No
• For any images presented appropriate consent has been obtained from the subjects. NA
PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Dec 01, 2023
• Manual Googling: Feb 27, 2025
• iThenticate Software: Mar 01, 2025 (10%)
ETYMOLOGY: Author Origin
EMENDATIONS: 8
- Emerging Sources Citation Index (Web of Science, thomsonreuters)
- Index Copernicus ICV 2017: 134.54
- Academic Search Complete Database
- Directory of Open Access Journals (DOAJ)
- Embase
- EBSCOhost
- Google Scholar
- HINARI Access to Research in Health Programme
- Indian Science Abstracts (ISA)
- Journal seek Database
- Popline (reproductive health literature)
- www.omnimedicalsearch.com