
Multifaceted Role of the Acellular Dermal Matrix in Novel Wound Healing: A Case Series
Correspondence Address :
Naveen Narayan,
No. 90, 14th Main, 14th Cross, 2nd Stage, 2nd Phase, West of Chord Road, Mahalakshmipuram, Bengaluru-560086, Karnataka, India.
E-mail: naveennumerouno@gmail.com
Acellular Dermal Matrix, Matriderm®, a collagen and elastin matrix, has emerged as a versatile tool in wound coverage, promoting healing and reducing scarring, thus offering numerous advantages in various clinical scenarios. The varied uses demonstrated here include concomitant application of the acellular dermal matrix while grafting with a full-thickness skin, application over bare bone in Split-Thickness Skin Grafting (STSG) and in the treatment of mucocutaneous fistulae in the oral cavity. The outcome with the use of Matriderm® in all these cases was satisfactory. Hereby, the authors present a case series of four patients that provide an understanding of Matriderm®’s efficacy in promoting healing and regeneration in complex wounds. Matriderm®, an acellular dermal matrix composed of collagen and elastin, supports tissue regeneration and reduces scarring, making it a valuable tool in complex wound management. The present case series highlights its versatility and potential in advancing wound care.
Matriderm®, Acellular dermal matrix, Bare bone, Full thickness wounds, Mucocutaneous fistula, Orocutaneous fistula, Skin substitute, Radiotherapy
DOI: 10.7860/JCDR/2025/79891.21070
Date of Submission: Apr 14, 2025
Date of Peer Review: Apr 22, 2025
Date of Acceptance: May 10, 2025
Date of Publishing: Jun 01, 2025
AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. Yes
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• Plagiarism X-checker: Apr 18, 2025
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ETYMOLOGY: Author Origin
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