Year :
2024
| Month :
July
| Volume :
18
| Issue :
7
| Page :
PD01 - PD03
Full Version
Takayasu Arteritis Presenting with Gangrene: A Case Report
Published: July 1, 2024 | DOI: https://doi.org/10.7860/JCDR/2024/71234.19576
Akash Inamdar, Pankaj Gharde, Raju Shinde, Abhilasha Bhargava
1. Junior Resident, Department of General Surgery, Acharya Vinoba Bhave Rural Hospital, Jawaharlal Nehru Medical College, DMIHER, Sawangi, Wardha, Maharashtra, India.
2. Professor, Department of General Surgery, Acharya Vinoba Bhave Rural Hospital, Jawaharlal Nehru Medical College, DMIHER, Sawangi, Wardha, Maharashtra, India.
3. Professor and Head, Department of General Surgery, Acharya Vinoba Bhave Rural Hospital, Jawaharlal Nehru Medical College, DMIHER, Sawangi, Wardha, Maharashtra, India.
4. Junior Resident, Department of General Surgery, Acharya Vinoba Bhave Rural Hospital, Jawaharlal Nehru Medical College, DMIHER, Sawangi, Wardha, Maharashtra, India.
Correspondence Address :
Dr. Akash Inamdar,
Junior Resident, Department of General Surgery, Acharya Vinoba Bhave Rural Hospital, Jawaharlal Nehru Medical College, DMIHER, Sawangi-442001, Wardha, Maharashtra, India.
E-mail: drakashinamdar@gmail.com
Abstract
Takayasu Arteritis (TA) is a chronic inflammatory disease affecting large blood vessels, particularly the aorta and its branches, making it a type of vasculitis. It is reported to be highly prevalent in Southeast Asian countries. Clinical presentations may vary, including headache, weight loss, malaise, fever, hypertension, visual disturbances, and musculoskeletal symptoms. Gangrene is a rare manifestation of TA, with relatively few cases reported globally. If gangrene is present, it is commonly noted in the lower limbs. Inflammation of the blood vessels caused by TA might lead to stenosis of the affected vessels. The underlying pathophysiology of gangrene development in TA is poorly understood but is mainly attributed to the occlusion of blood vessels. It is associated with inflammatory markers produced by lymphocytes and macrophages. Immunosuppressive drugs are recommended for symptomatic relief. Early diagnosis and intervention can be useful in managing TA, preventing adverse outcomes, and reducing its financial, social, and psychological consequences. This is a case report of a 32-year-old female, presented with gangrene and a history of rheumatoid arthritis. Further examination revealed a presentation of TA. The patient was managed by below-knee amputation for gangrene of the left leg and medical management for TA. Therefore, authors aim to draw attention to the diagnosis of TA and the rare associated morbidity, ‘gangrene,’ and the importance of timely intervention.
Keywords
Below knee amputation, Critical limb ischaemia, Limb claudication, Pulselessness, Vasculitis
DOI: 10.7860/JCDR/2024/71234.19576
Date of Submission: Apr 13, 2024
Date of Peer Review: Apr 29, 2024
Date of Acceptance: May 27, 2024
Date of Publishing: Jul 01, 2024.
AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was informed consent obtained from the subjects involved in the study? No
• For any images presented appropriate consent has been obtained from the subjects. Yes
PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Apr 13, 2024
• Manual Googling: Apr 30, 2024
• iThenticate Software: May 25, 2024 (3%)
ETYMOLOGY: Author Origin
EMENDATIONS: 5
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