Mastication Frequency and Postprandial Blood Sugar Levels in Normoglycaemic and Dysglycaemic Individuals: A Cross- Sectional Comparative study
Published: July 1, 2016 | DOI: https://doi.org/10.7860/JCDR/2016/.8082
Vinayak Madhu, Arun Shirali, Priyanka Niwas Pawaskar,
Deepak Madi, Nithyananda Chowta, John Thomas Ramapuram
1. Junior Resident, Department of Medicine, Kasturba Medical College, Manipal University, Mangalore, India.
2. Associate Professor, Department of Medicine, Kasturba Medical College, Manipal University, Mangalore, India.
3. Assistant Professor, Department of Physiology, Kanachur Institute of Medical Sciences, Mangalore, India.
4. Associate Professor, Department of Medicine, Kasturba Medical College, Manipal University, Mangalore, India.
5. Additional Professor, Department of Medicine, Kasturba Medical College, Manipal University, Mangalore, India.
6. Professor, Department of Medicine, Kasturba Medical College, Mangalore, Manipal University, Mangalore, India.
Correspondence Address :
Dr. Arun Shirali,
Associate Professor, Department of Internal Medicine, KMC – Attavar, Manipal University, Mangalore, India.
E-mail: drarunshirali@gmail.com
Abstract
Introduction: Mastication has potential to affect postprandial blood glucose levels by affecting cephalic phase of insulin release. However, limited number of studies done in this regard has yielded conflicting results.
Aim: To evaluate effects of mastication on postprandial blood glucose levels.
Materials and Methods: We compared routine and thorough mastication in 2 separate groups: dysglycaemic (prediabetics and diabetics) and normoglycaemic in prospective interventional study. Blood glucose levels were measured pre-prandial and postprandial (after 2 hours) on separate days after routine and thorough mastication in both groups.
Results: In normoglycaemic group, thorough mastication significantly reduced postprandial blood glucose levels at 2 hours (128.25± 7.82 mg/dl on routine mastication vs 119.74±9.08 mg/dl on thorough mastication, p<0.05). Comparatively, in dysglycaemic group, thorough mastication had little effect on postprandial blood glucose levels at 2 hours (244.07±22.37 mg/dl vs. 243.55±22.87 mg/dl).
Conclusion: In normoglycaemic group, postprandial blood glucose concentration upon thorough mastication was significantly lower, due to early-phase insulin secretion. This simple lifestyle modification of thorough mastication can be a useful preventive measure against diabetes in people with a strong family history and other risk factors for diabetes who have not yet developed diabetes or prediabetes.
Keywords
Diabetics, Plasma glucose levels, Pre-diabetics, Rate of chewing