Pregnancy with Pemphigoid Gestationis: A Rare Entity
Published: July 1, 2016 | DOI: https://doi.org/10.7860/JCDR/2016/.8215
Anshuja Singla, Sneha Shree, Sumita Mehta
1. Assistant Professor, Department of Obstetrics and Gynecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
2. Senior Resident, Department of Obstetrics and Gynecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
3. Senior Specialist, Department of Obstetrics and Gynecology, Babu Jagjivan Ram Hospital, Delhi, India.
Correspondence Address :
Dr. Anshuja Singla,
Assistant Professor, Department of Obstetrics and Gynecology,
University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi-110095, India.
E-mail: dranshuja@gmail.com
Abstract
Pemphigoid Gestationis (PG) is a rare autoimmune blistering disease with an incidence of 1/50000 pregnancies. Presentation in the second or third trimester is most common and tends to recur in subsequent pregnancies with earlier onset and a more severe course. Direct Immunofluorescence (DIF) staining is confirmatory on skin biopsy specimen. A 24-year-old female presented at 6 months period of gestation with increased blood pressure records. On examination, there were fresh bullous lesions along with old healed scar marks on the abdomen and limbs. Termination of pregnancy was done due to high BP. Patient delivered a fresh still birth weighing 750 gm. No postpartum flare ups were seen and she was discharged on prednisolone in a satisfactory condition.
Keywords
Autoimmune, Dermatosis, Direct immunofluorescence, Prednisolone, Pruritus