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Role of Interleukin-33 in Immunity and Periodontal Inflammation-A Literature Review
ZE08-ZE10
Correspondence
Dr. Karuppanan Sasi Kumar,
Reader, Department of Periodontics, JKKN Dental College and Hospitals, Komarapalayam, Namakkal District,
Erode, Tamil Nadu-638315, India.
E-mail: sasikumar@jkkn.org
The Interleukin-33 (IL-33) is a member of IL-1 family discovered in the year of 2005. The Interleukin-1 (IL-1) family of cytokines is commonly encountered in chronic inflammatory diseases such as rheumatoid arthritis and periodontitis. IL-33 regulates the innate and adaptive immunity and it also participates in initiation and progression of periodontal diseases. The aim of this review was to analyse the biological and immunological role of IL-33 in progression of periodontal diseases. This review also deals with the IL-33 signaling pathway in the periodontal inflammation.