Moyamoya Syndrome with Recurrent Stroke in a Splenectomised Patient with Beta-Thalassaemia Major: A Case Report
TD04-TD06
Correspondence
Vijetha Chanabasanavar,
Junior Resident, Department of Radiodiagnosis, Dr. D. Y. Patil Vidyapeeth Medical
College and Research Centre, Pimpri, Pune, Maharashtra, India.
E-mail: vijethachanabasanavar@gmail.com
Moyamoya Syndrome (MMS) is a progressive disease with typical angiographic ‘moyamoya’ alterations. Here, the authors discuss a case of 16-year-old male patient who developed MMS after being diagnosed with ß-thalassaemia major. This patient was detected with heterozygous mutations in the ß-globin gene and underwent splenectomy at the age of 12 years. Four years postsplenectomy he presented with paresis of the right upper limb. Magnetic Resonance Imaging (MRI) showed infarction and stenosis of the internal carotid artery with the collateral vessel’s formation. Recurrence of stroke and progression of the vasculopathy were seen. Till now, only a few cases of MMS have been linked to thalassaemia major.