Study
of Multidrug Resistant (MDR) Isolates
in Patients with Ventilator Associated
Pneumonia in a Rural Hospital
1363-1366
Correspondence
Santosh Kotgire
Assistant professor
Deptt of Microbiology
Dr.Ulhas Patil Medical College
Jalgaon,Maharashtra.
Phone: +919922867658
E-mail: santosh_kots2001@yahoo.com
Background and Objective: The identification of microorganisms which cause ventilator associated pneumonia (VAP) is important for formulating appropriate therapies. In this study, we have reported the incidence of VAP and the prevalence of multidrug resistant (MDR) microorganisms from patients who were diagnosed with VAP in our medical-surgical intensive care unit during the period from August 07 to May 08.
Material and Methods: Patients who were on mechanical ventilation for more than 48hrs and in whom ventilator associated pneumonia was suspected, when a new and persistent pulmonary infiltrate appeared on the chest radiograph and who had at-least two of the following criteriae, were included in the study: 1. Fever ≥38˚C or hypothermia ≤36˚C 2. WBC count ≥ 10000mm3 or ≤ 4000 mm3 and 3. Purulent tracheal secretion.
Results: The incidence of VAP in our hospital setting was found to be 45% and the most frequently isolated pathogens were Pseudomonas spp, Staphylococcus aureus and members of the family, Enterobacteriacae. Of the 73 isolates which were studied, 36 were found to be MDR .
Conclusion: In conclusion, the incidence of VAP and the prevalence of multidrug resistant microorganisms were quite high in our ICU setup. A local surveillance program at each centre is essential, as the knowledge of local resistant patterns is vital for selecting the appropriate agents for treating infections.