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Different features in Wegener’s Granulomatosis: Report of five cases
1437-1439
Correspondence
Mehrdad Aghaie
5th Azar hospital, 5th Azar street, Gorgan,
Golestan province, Iran.
Tel. +98 171 2230230
Fax. +98 171 2228363
Email: mehrdadaghaie@yahoo.com
Wegener’s granulomatosis (WG) is an autoimmune inflammatory condition. It is often a rapidly progressive and potentially fatal disease. The clinical presentation of WG can be so diverse that the list of its differential diagnosis is vast, ranging from infectious diseases to other vasculitis (e.g. Behcet’s disease), as well as malignancies. The exact aetiology of WG remains unclear. The upper airway diseases including sinusitis, oral lesions and otitis media are the most common presenting features of WG. In this paper, we have described 5 WG cases. They had different presentations and chief complaints. Some of them presented with upper airways diseases, while the others mainly suffered from the manifestations of pulmonary involvement. Although all of them were finally diagnosed as WG cases, the processes of the work up for the diagnosis as well as the outcome of the disease were not the same. So, the diversities in the presentation should be mentioned in the management of the WG suspected patients.