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Complete Mouth Rehabilitation in a Patient with Fanconi Anaemia: A Rare Genetic Disorder
SD04-SD06
Correspondence
Dr. Sonali Vedraj Sharma,
Lecturer, Department of Biomedical Dental Sciences (Oral Medicine Division), College of Dentistry, Imam Abdulrahman bin Faisal University, Dammam, Kingdom of Saudi Arabia-31441, Eastern Province, Saudi Arabia.
E-mail: svsharma@iau.edu.sa
Fanconi anaemia is a rare, progressive congenital bone marrow failure syndrome characterised by autosomal recessive inheritance and clinical manifestations, including growth retardation, bone marrow failure leading to pancytopenia, an elevated risk of malignancy, skin pigmentation, and skeletal malformations. Patients who have undergone bone marrow transplantation can be treated comprehensively in the dental clinic like other routine patients, provided their blood indices are within normal limits. Its complications include aplastic anaemia, malignancies like acute myeloid leukaemia, liver tumours, and squamous cell carcinoma, often developing post-bone marrow transplantation. Dental anomalies, altered salivary flow, and increased susceptibility to cancer necessitate early diagnosis and specialised dental care. Hereby, the authors present a case of 15-year-old male with Fanconi Anaemia who had undergone bone marrow transplantation and was treated comprehensively in a hospital setting. The present case report aimed to equip healthcare practitioners, especially dentists, with the knowledge needed for accurate diagnosis and effective management.