Disseminated Langerhans Cell Histiocytosis Presenting as Cholestatic Jaundice
SD03-SD05
Correspondence
Dr. Rohit Kapoor,
86-A GTB Enclave Opp. GTB Hospital F- Pocket New Delhi-10093, India.
E-mail: rohitvmmc@gmail.com
Langerhans cell histiocytosis (LCH) is a disorder associated with proliferation of Langerhans cells in various organs. LCH secondary to multisystem involvement can present in a variety of ways. Because of its infiltrative nature, LCH can involve the skin, lymph nodes, the lung or the liver. Jaundice in LCH is a manifestation of liver disease; biliary dilatation secondary to lithiasis or may be due to coexistent Niemann-Pick disease. However, a case of cholestasis has been very rarely described. Cholestasis may result from lymph nodes obstructing the porta hepatis. In this report, we describe a case of type II histiocytosis X with obstructive cholestasis and pulmonary involvement in the form of cysts without significant lymphadenopathy at the porta.