Lipase And Ca2+ Ions As Biomarkers In Blood Serum Of NIDDM 942-945
Dr. Verma N, Department of Biotechnology, Punjabi University, Patiala, India.Tel: 9815710298 Email:firstname.lastname@example.org email@example.com
Non Insulin Dependent Diabetes Mellitus (NIDDM) is a metabolic disease characterized by insulin resistance, hyperglycemia, often associated with hypertension, lipid disturbances and obesity. Blood serum of normal healthy subject and NIDDM patients are considered for study. Lipase and Ca2+ ions concentrations have been compared in NIDDM and normal healthy subjects along with glucose concentration. Lipase activity is increased (287-325 U/L) in blood serum of NIDDM than normal healthy range (30-250 U/L). Ca2+ ions concentration has been decreased (1.5-3.4 mg/dL) below the normal range (8.9-10.4 mg / dL ). Hence lipase can be used as a biomarker for disease diagnosis and low Ca2+ ions concentrations observed in NIDDM may be alarming leading to multiple diseases.