Lipid Profile In Preeclampsia – A Case Control Study 2748-2751
Department of Biochemistry
S.Nijalingappa Medical college
Navanagar, Bagalkot â€“ 587102
Email : email@example.com
Background and Objectives: According to the current knowledge, rise in the serum triglycerides level is a major contributor in the pathogenesis of pre-eclampsia. In this context, this study was undertaken to compare the changes in lipid profile in normal pregnancy and in pre-eclampsia.
Method: A Case control study was done consisting of 90 pre-eclamptic (cases) and 90 healthy pregnant women(controls). Fasting venous blood samples were collected during ante partum period and serum levels of Triglycerides (TG), Total cholesterol (TC),low density lipoprotein cholesterol (LDL-C), very low density lipoprotein cholesterol(VLDL-C), high density lipoprotein cholesterol (HDL-C) were measured.
Results : In the pre-eclamptic group serum triglyceride (193.37Â±43.93 mg/dl) was increased significantly (P<0.001) as compared to normal pregnant women. Other parameters TC,LDL-C,VLDL-C and HDL-C were not raised significantly. There is a positive correlation between serum triglycerides and systolic blood pressure and diastolic blood pressure in pre eclampsia cases.
Interpretation and Conclusion : The findings of the present study are consistent with previous studies, suggesting high levels of serum triglycerides as an important factor in the pathogenesis of pre -eclampsia.